Precision medicine is making an impact on patients, health care delivery systems, and
research participants in ways that were only imagined fifteen years ago when the human …

The implementation of pharmacogenomic (PGx) testing in psychiatry remains modest, in part
due to divergent perceptions of the quality and completeness of the evidence base and …

Aim: To conducted a systematic review and meta-analysis of prospective, randomized
controlled trials (RCTs) that examined pharmacogenetic-guided decision support tools …

Introduction The heterogeneity of symptoms and complex etiology of depression pose a
significant challenge to the personalization of treatment. Meanwhile, the current application …

Objectives Precision medicine (PM) aims to improve patient outcomes by stratifying or
individualizing diagnosis and treatment decisions. Previous reviews found inconclusive …

Pharmacogenomics (PGx) is the study of genetic influences on an individual's response to
medications. Improvements in the quality and quantity of PGx research over the past two …

Background Clinical pharmacogenomics uses genetic information to guide optimal drug
selection and drug dosing for patients to maximize therapeutic effects, improve outcomes …

In Dr. Francis Collins' 2001 testimony to Congress, he heralded advances in genetics with
the Human Genome Project. He imagined testing “being used to tailor medicines to fit …

Nowadays, many relevant drug–gene associations have been discovered, but
pharmacogenomics (PGx)-guided treatment needs to be cost-effective as well as clinically …

Purpose To examine the evidence on the cost-effectiveness of implementing
pharmacogenomics (PGx) in cardiovascular disease (CVD) care. Methods We conducted a …