Pentoxifylline alleviates early brain injury after experimental subarachnoid hemorrhage in rats: Possibly via inhibiting TLR 4/NF-κB signaling pathway

D Xia, H Zhang, L Wu, X Zhang, M Zhou… - Neurochemical research, 2017 - Springer
Early brain injury (EBI) after subarachnoid hemorrhage (SAH) generally causes significant
and lasting damage. Pentoxifylline (PTX), a nonselective phosphodiesterase inhibitor, has …

A neuroprotective effect of pentoxifylline in rats with diabetic neuropathy: Mitigation of inflammatory and vascular alterations

RAM Salama, FA Raafat, AH Hasanin… - International …, 2024 - Elsevier
Background Treatment of diabetic neuropathic pain does not change the natural history of
neuropathy. Improved glycemic control is the recommended treatment in these cases, given …

[HTML][HTML] The Effect of Local Papaverine Use in an Experimental High-Risk Colonic Anastomosis Model: Reduced Inflammatory Findings and Less Necrosis

DB Ozdemir, A Karayigit, E Tekin, E Kocaturk… - Journal of Clinical …, 2024 - mdpi.com
Objectives: To assess the impact of topical papaverine administration in complete and
incomplete colonic anastomosis, by examining bursting pressure, hydroxyproline …

[HTML][HTML] The effects of vardenafil and pentoxifylline administration in an animal model of ischemic colitis

M Aziret, O Irkorucu, E Reyhan, H Erdem, K Das… - Clinics, 2014 - SciELO Brasil
OBJECTIVES: Vardenafil enhances dilatation of vascular smooth muscle and inhibits
platelet aggregation. The purpose of this study was to evaluate the clinical effects of …

Effects of pentoxifylline administration on histomorphological parameters of streptozotocin-induced diabetic rat testes

A Piryaei, A Najar, M Bayat - Laboratory Animal Research, 2015 - Springer
The effect of pentoxifylline (PTX) administration on histomorphological parameters of
streptozotocin (STZ)-induced type 1 diabetes mellitus (DM) in male rat testes were …

[HTML][HTML] The effect of papaverine on tendon healing and adhesion in rats following Achilles tendon repair

E Can, YM Dincel, D Karabulut, S Karabag… - Joint Diseases and …, 2024 - ncbi.nlm.nih.gov
Objectives The study aimed to examine the histopathological and biomechanical effects of
papaverine administered intraperitoneally and locally on Achilles tendon healing in a rat …

Fabrication of pentoxifylline-loaded hydroxyapatite/alginate scaffold for bone tissue engineering

M Shadravanan, M Latifi, Z Vojdani… - Journal of Biomimetics …, 2020 - Trans Tech Publ
Background: Hydroxyapatite (HAP), as a common biomaterial in bone tissue engineering,
can be fabricated in combination with other osteogenic agents. Pentoxifylline (PTX) is …

The effect of three different surgical techniques for colon anastomosis on regional postoperative microperfusion: Laser Doppler Flowmetry study in pigs

M Kaska, S Blazej, Z Turek, A Ryska… - Clinical …, 2018 - content.iospress.com
BACKGROUND: The optimal surgical approach to reconnecting bowel ends safely after
resection is of great importance. OBJECTIVES: This project is focused on assessment of the …

Effects of papaverine on healing of colonic anastomosis in rats

SI Basceken, Y Sevim, C Akyol, E Cicek, F Aydın… - European Surgery, 2017 - Springer
Background Anastomotic leak is the most devastating complication after colorectal surgery,
and the blood supply is a very important factor in anastomotic healing. Papaverine is a …

Examining the safety of colon anastomosis on a rat model of ischemia-reperfusion injury

D Czeiger, A Osyntsov, L Osyntsov, CG Ball… - World Journal of …, 2013 - Springer
Introduction Intestinal ischemia and reperfusion can impair anastomotic strength. The
purpose of this study was to evaluate the safety of delayed colon anastomosis following …