[HTML][HTML] Current Technologies Unraveling the Significance of Post-Translational Modifications (PTMs) as Crucial Players in Neurodegeneration

S Zafar, SI Fatima, M Schmitz, I Zerr - Biomolecules, 2024 - mdpi.com
Neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, and
Huntington's disease, are identified and characterized by the progressive loss of neurons …

[HTML][HTML] PTMs of PD-1/PD-L1 and PROTACs application for improving cancer immunotherapy

X Ren, L Wang, L Liu, J Liu - Frontiers in Immunology, 2024 - frontiersin.org
Immunotherapy has been developed, which harnesses and enhances the innate powers of
the immune system to fight disease, particularly cancer. PD-1 (programmed death-1) and PD …

[HTML][HTML] Oxidative Cysteine Post Translational Modifications Drive the Redox Code Underlying Neurodegeneration and Amyotrophic Lateral Sclerosis

A Percio, M Cicchinelli, D Masci, M Summo, A Urbani… - Antioxidants, 2024 - mdpi.com
Redox dysregulation, an imbalance between oxidants and antioxidants, is crucial in the
pathogenesis of various neurodegenerative diseases. Within this context, the “redoxome” …

[PDF][PDF] Pazopanib: Effective monotherapy for precise cancer treatment, targeting specific mutations and tumors

R Pathak, V Kaur, S Sharma, M Bhandari, R Mishra… - Cancer, 2024 - researchgate.net
Cancer is a wide range of illnesses characterized by the expansion of abnormal cells with
the ability to invade and damage healthy bodily tissue. Cancer is treated with a variety of …

Neddylation-related gene signature predicts the prognosis and is associated with immune infiltration of glioma

Z Jiang, W Yin, G Tang, Y Guo, HL Huang, Z Wang… - 2024 - researchsquare.com
Background Glioma is the most prevalent malignant tumor that originates from central
nervous system. Neddylation, a post-translational modification similar to ubiquitination, is …