European association of urology guidelines on male sexual and reproductive health: 2021 update on male infertility

S Minhas, C Bettocchi, L Boeri, P Capogrosso… - European urology, 2021 - Elsevier
Abstract Context The European Association of Urology (EAU) has updated its guidelines on
sexual and reproductive health for 2021. Objective To present a summary of the 2021 …

EAA/EMQN best practice guidelines for molecular diagnosis of Y‐chromosomal microdeletions: state‐of‐the‐art 2013

C Krausz, L Hoefsloot, M Simoni, F Tüttelmann - Andrology, 2014 - Wiley Online Library
The molecular diagnosis of Y‐chromosomal microdeletions is a common routine genetic test
which is part of the diagnostic workup of azoospermic and severe oligozoospermic men …

European Association of Urology guidelines on Male Infertility: the 2012 update

A Jungwirth, A Giwercman, H Tournaye, T Diemer… - European urology, 2012 - Elsevier
CONTEXT: New data regarding the diagnosis and treatment of male infertility have emerged
and led to an update of the European Association of Urology (EAU) guidelines for Male …

Genetics of azoospermia

F Cioppi, V Rosta, C Krausz - International Journal of Molecular Sciences, 2021 - mdpi.com
Azoospermia affects 1% of men, and it can be due to:(i) hypothalamic-pituitary
dysfunction,(ii) primary quantitative spermatogenic disturbances,(iii) urogenital duct …

Genetics of male infertility

C Krausz, V Rosta, RS Swerdloff, C Wang - Emery and rimoin's principles …, 2022 - Elsevier
Approximately 7% of men suffer from fertility problems, the etiology of which are ascribable
to a number of factors acting at pretesticular, posttesticular, or testicular levels. About 20% of …

Male infertility: pathogenesis and clinical diagnosis

C Krausz - Best practice & research Clinical endocrinology & …, 2011 - Elsevier
Infertility affects about 7% of all men. The etiology of impaired sperm production and function
can be related to factors acting at pre-testicular, post-testicular or directly at the testicular …

The evolving role of genetic tests in reproductive medicine

F Cariati, V D'Argenio, R Tomaiuolo - Journal of translational medicine, 2019 - Springer
Infertility is considered a major public health issue, and approximately 1 out of 6 people
worldwide suffer from infertility during their reproductive lifespans. Thanks to technological …

Molecular and clinical characterization of Y chromosome microdeletions in infertile men: a 10-year experience in Italy

A Ferlin, B Arredi, E Speltra… - The Journal of …, 2007 - academic.oup.com
Context: An explosive growth in Y chromosome long arm (Yq) microdeletion testing demand
for male infertility occurred in the past few years. However, despite the progresses in the …

Spermatogenic failure and the Y chromosome

C Krausz, E Casamonti - Human genetics, 2017 - Springer
The Y chromosome harbors a number of genes essential for testis development and
function. Its highly repetitive structure predisposes this chromosome to deletion/duplication …

State of the art for genetic testing of infertile men

RI McLachlan, MK O'Bryan - The Journal of Clinical …, 2010 - academic.oup.com
Intracytoplasmic sperm injection (ICSI) now provides fertility in many cases of severe
idiopathic spermatogenic failure and obstructive azoospermia. Genetic causes must be …