Nanosystem trends in drug delivery using quality-by-design concept

J Li, Y Qiao, Z Wu - Journal of Controlled Release, 2017 - Elsevier
Quality by design (QbD) has become an inevitable trend because of its benefits for product
quality and process understanding. Trials have been conducted using QbD in nanosystems' …

Micellar solubilization of poorly water-soluble drugs: effect of surfactant and solubilizate molecular structure

Z Vinarov, V Katev, D Radeva… - Drug development …, 2018 - Taylor & Francis
Objective: This study aims to clarify the role of surfactant and drug molecular structures on
drug solubility in micellar surfactant solutions. Significance:(1) Rationale for surfactant …

Enhanced solubilization of curcumin in mixed surfactant vesicles

A Kumar, G Kaur, SK Kansal, GR Chaudhary… - Food Chemistry, 2016 - Elsevier
Self-assemblies of equimolar double and single chain mixed ionic surfactants, with
increasing numbers of carbon atoms of double chain surfactant, were analyzed on the basis …

Inorganic salt-induced micellar morphologies in deep eutectic solvent: Structure and curcumin solubilization

D Hirpara, V Chavda, N Hirapara, S Kumar - Journal of Molecular Liquids, 2024 - Elsevier
Physico-spectroscopic data of deep eutectic solvent (DES, aquolines (choline chloride,
ChCl: water (1: 2 (DES I), 1: 3 (DES II), 1: 4 (DES III), and 1: 5 (DES IV)) have been collected …

Novel surface-active ionic liquids used as solubilizers for water-insoluble pesticides

T Fan, C Chen, T Fan, F Liu, Q Peng - Journal of Hazardous Materials, 2015 - Elsevier
Three surface active ionic liquids (ILs) containing organic anions but no halides were used
as solubilizers for water insoluble pesticides and as well as alternates for similar ILs with …

[HTML][HTML] Experimental investigation of dynamic drying in single pharmaceutical granules containing acetaminophen or carbamazepine using synchrotron X-ray micro …

C Blocka, XF Ding, N Zhu, L Zhang - International Journal of Pharmaceutics, 2024 - Elsevier
Drying time, velocity, and temperature are important aspects of the drying process for
pharmaceutical granules observed during tablet manufacturing. However, the drying …

Solubilization and co-solubilization of carbamazepine and nifedipine in mixed micellar systems: insights from surface tension, electronic absorption, fluorescence and …

M Maswal, OA Chat, S Jabeen, U Ashraf, R Masrat… - RSC …, 2015 - pubs.rsc.org
UV absorption spectral and HPLC study on the solubilization and co-solubilization behavior
of antiepileptic drug Carbamazepine (CBZ) and calcium channel blocker Nifedipine (NFD) …

Mechanistic Investigation of Drug Supersaturation in the Presence of Polysorbates as Solubilizing Additives by Solution Nuclear Magnetic Resonance Spectroscopy

X Lu, M Li, FA Arce, J Ling, N Setiawan… - Molecular …, 2021 - ACS Publications
The introduction of solubilizing additives has historically been an attractive approach to
address the ever-growing proportion of poorly water-soluble drug (PWSD) compounds …

The versatile dioctadecyldimethylammonium bromide

AM Carmona-Ribeiro - Application and Characterization of …, 2017 - books.google.com
Dioctadecyldimethylammonium bromide (DODAB) is a quaternary ammonium surfactant
(Quat) with interesting properties and applications. In this chapter, DODAB characteristics as …

Co-solubilization of polycyclic aromatic hydrocarbon mixtures in aqueous micellar systems and its correlation with FRET for enhanced remediation processes

U Ashraf, MS Lone, R Masrat, RA Shah, S Afzal… - Chemosphere, 2020 - Elsevier
Surfactant enhanced remediation (SER) is an effective approach for decontaminating the
PAH polluted soils. Solubilization and Cosolubilization of Phenanthrene (Ph), Pyrene (Py) …