The delayed and prolonged postmitotic maturation of human neurons, compared with
neurons from other species, may contribute to human-specific cognitive abilities and …

NMDA receptors (NMDARs), a prominent subtype of glutamatergic receptors, are implicated
in the pathogenesis and development of neuropsychiatric disorders such as epilepsy …

One of the hallmarks of the cerebral cortex is the extreme diversity of interneurons,–. The two
largest subtypes of cortical interneurons, parvalbumin-and somatostatin-positive cells, are …

Mammalian neocortical neurons span one of the most diverse cell type spectra of any tissue.
Cortical neurons are born during embryonic development, and their maturation extends into …

During postnatal development, the DNA methyltransferase DNMT3A deposits high levels of
non-CG cytosine methylation in neurons. This methylation is critical for transcriptional …

In most animals, the majority of the nervous system is generated and assembled into
neuronal circuits during embryonic development. However, during juvenile stages, nervous …

5-Methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are the most abundant DNA
modifications that have important roles in gene regulation. Detailed studies of these different …

Proper assembly and function of the nervous system requires the generation of a uniquely
diverse population of neurons expressing a cell-type-specific combination of effector genes …

Neurons born in the embryo can undergo a protracted period of maturation lasting well into
postnatal life. How gene expression changes are regulated during maturation and whether …

HIV-1 encounters the hierarchically organized host chromatin to stably integrate and persist
in anatomically distinct latent reservoirs. The contribution of genome organization in HIV-1 …