Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

Social circuits and their dysfunction in autism spectrum disorder

M Sato, N Nakai, S Fujima, KY Choe, T Takumi - Molecular Psychiatry, 2023 - nature.com
Social behaviors, how individuals act cooperatively and competitively with conspecifics, are
widely seen across species. Rodents display various social behaviors, and many different …

Neural control of affiliative touch in prosocial interaction

YE Wu, J Dang, L Kingsbury, M Zhang, F Sun, RK Hu… - Nature, 2021 - nature.com
The ability to help and care for others fosters social cohesiveness and is vital to the physical
and emotional well-being of social species, including humans,–. Affiliative social touch, such …

Neural circuits of social behaviors: Innate yet flexible

D Wei, V Talwar, D Lin - Neuron, 2021 - cell.com
Social behaviors, such as mating, fighting, and parenting, are fundamental for survival of any
vertebrate species. All members of a species express social behaviors in a stereotypical and …

Social agent identity cells in the prefrontal cortex of interacting groups of primates

R Báez-Mendoza, EP Mastrobattista, AJ Wang… - Science, 2021 - science.org
INTRODUCTION Social groups play a foundational role in the behavior of many animal
species. During group interactions, an individual's behavior can affect not only the well …

Cortical regulation of helping behaviour towards others in pain

M Zhang, YE Wu, M Jiang, W Hong - Nature, 2024 - nature.com
Humans and animals exhibit various forms of prosocial helping behaviour towards others in
need,–. Although previous research has investigated how individuals may perceive others' …

Loneliness and the social brain: how perceived social isolation impairs human interactions

J Lieberz, SG Shamay‐Tsoory, N Saporta… - Advanced …, 2021 - Wiley Online Library
Loneliness is a painful condition associated with increased risk for premature mortality. The
formation of new, positive social relationships can alleviate feelings of loneliness, but …

Ventromedial prefrontal neurons represent self-states shaped by vicarious fear in male mice

Z Huang, M Chung, K Tao, A Watarai, MY Wang… - Nature …, 2023 - nature.com
Perception of fear induced by others in danger elicits complex vicarious fear responses and
behavioral outputs. In rodents, observing a conspecific receive aversive stimuli leads to …

Beyond cortex: The evolution of the human brain.

R Chin, SWC Chang, AJ Holmes - Psychological Review, 2023 - psycnet.apa.org
Human evolution has been marked by a striking increase in total brain volume relative to
body size. While a prominent and characteristic feature of this volumetric shift has been the …

The role of the prefrontal cortex in social interactions of animal models and the implications for autism spectrum disorder

AN Mohapatra, S Wagner - Frontiers in Psychiatry, 2023 - frontiersin.org
Social interaction is a complex behavior which requires the individual to integrate various
internal processes, such as social motivation, social recognition, salience, reward, and …