Skin tissue regeneration for burn injury

A Shpichka, D Butnaru, EA Bezrukov… - Stem cell research & …, 2019 - Springer
The skin is the largest organ of the body, which meets the environment most directly. Thus,
the skin is vulnerable to various damages, particularly burn injury. Skin wound healing is a …

Mesenchymal stem cells for chronic wound healing: current status of preclinical and clinical studies

YZ Huang, M Gou, LC Da, WQ Zhang… - Tissue Engineering Part …, 2020 - liebertpub.com
Healing skin wounds with anatomic and functional integrity, especially under chronic
pathological conditions, remain an enormous challenge. Due to their outstanding …

3D protein-based bilayer artificial skin for the guided scarless healing of third-degree burn wounds in vivo

M Gholipourmalekabadi, AM Seifalian… - …, 2018 - ACS Publications
Severe burn injuries can lead to delays in healing and devastating scar formation. Attempts
have been made to develop a suitable skin substitute for the scarless healing of such skin …

Application of adipose-tissue derived products for burn wound healing

H Malekzadeh, Z Tirmizi, JA Arellano, FM Egro, A Ejaz - Pharmaceuticals, 2023 - mdpi.com
Burn injuries are a significant global health concern, leading to high morbidity and mortality.
Deep burn injuries often result in delayed healing and scar formation, necessitating effective …

Efficacy of stem cell therapy for burn wounds: a systematic review and meta-analysis of preclinical studies

Y Li, W Xia, L Van der Merwe, W Dai, C Lin - Stem cell research & therapy, 2020 - Springer
Background Burns remain a serious public health problem with high morbidity and mortality
rates worldwide. Although there are various treatment options available, there is no …

Stem cells in burn wound healing: A systematic review of the literature

AR Ahmadi, M Chicco, J Huang, L Qi, J Burdick… - Burns, 2019 - Elsevier
Introduction Severe burns are often associated with high morbidity and unsatisfactory
functional and esthetic outcomes. Over the last two decades, stem cells have generated …

Combination of platelet rich plasma and stromal vascular fraction on the level of vascular endothelial growth factor in rat subjects experiencing deep dermal burn …

SR Laidding, F Josh, S Battung, A Bukhari… - Annals of Medicine …, 2021 - journals.lww.com
Background: The healing process of burns includes coagulation, inflammation, and
remodeling. Vascular endothelial growth factor (VEGF) is involved throughout this healing …

Cellular therapies for treatment of radiation injury: report from a NIH/NIAID and IRSN workshop

AL DiCarlo, R Tamarat, CI Rios… - Radiation …, 2017 - meridian.allenpress.com
In recent years, there has been increasing concern over the possibility of a radiological or
nuclear incident occurring somewhere in the world. Intelligence agencies frequently report …

Autologous adipose-derived regenerative cell therapy modulates development of hypertrophic scarring in a red Duroc porcine model

P Foubert, D Zafra, M Liu, R Rajoria, D Gutierrez… - Stem cell research & …, 2017 - Springer
Background Effective prevention and treatment of hypertrophic scars (HTSs), a common
consequence of deep-partial thickness injury, remain a significant clinical challenge …

Preclinical assessment of safety and efficacy of intravenous delivery of autologous adipose-derived regenerative cells (ADRCs) in the treatment of severe thermal …

P Foubert, M Liu, S Anderson, R Rajoria, D Gutierrez… - Burns, 2018 - Elsevier
Objective A number of studies have reported that application of autologous adipose-derived
cell populations leads to improved outcome in different preclinical models of thermal burn …