Abstract miRNAs are small non-coding RNA molecules that modulate the expression of
multiple protein-encoding genes at the post-transcriptional level. They have recently been …

Systemic lupus erythematosus (SLE) is a typical autoimmune disease with a complex
pathogenesis and genetic predisposition. With continued understanding of this disease, it …

Allogeneic mesenchymal stem cells (MSCs) exhibit immunoregulatory function in human
autoimmune diseases such as systemic lupus erythematosus (SLE), but the underlying …

Nearly one trillion platelets circulate in the blood to monitor and preserve the integrity of the
vasculature. However, haemostasis is not their only function. Platelets are also potent …

There is increasing interest by physicians in the impact of the innate immune system on
human diseases. In particular, the role of the molecules that initiate and amplify innate …

Objective Systemic lupus erythematosus (SLE), the most common form of lupus, is a
multisystemic rheumatic disease with different clinical features that generally affect women …

In this prospective, cross-sectional, multicenter study, we assessed clinical and laboratory
characteristics from patients with cutaneous lupus erythematosus (CLE) using the Core Set …

Dendritic cells (DCs) are professional antigen presenting cells displaying the unique
capability to activate naïve T cells. DCs react to pathogen encounter also by the production …

Nuclear receptors are ligand-activated transcription factors linking lipid signaling to the
expression of the genome. There is increasing appreciation of the involvement of this …

Systemic lupus erythematosus (SLE) is a multisystemic, autoimmune disease,
encompassing either mild or severe manifestations. SLE was originally labeled as being an …