Despite the success of targeted therapies in cancer treatment, therapy-induced resistance
remains a major obstacle to a complete cure. Tumor cells evade treatments and relapse via …

Cholangiocarcinoma (CCA) encompasses a group of malignancies that can arise at any
point in the biliary tree. Although considered a rare cancer, the incidence of CCA is …

Glypican-3 (GPC3) is a membrane-associated proteoglycan that is specifically up-regulated
in hepatocellular carcinoma (HCC) although rarely or not expressed in normal liver tissues …

Gastrointestinal (GI) cancers with a high incidence rate and adverse complications are
related to severe morbidity and mortality around the world. MicroRNAs (miRs) are potential …

Most tumors develop abnormal fibrotic regions consisting of fibroblasts, immune cells, and a
dense extracellular matrix (ECM) immersed in a viscous interstitial fluid, and an abundant …

Hair follicle stem cells (HFSCs) reside in the bulge region of the outer root sheath of the hair
follicle. They are considered slow-cycling cells that are endowed with multilineage …

Wumei Pill (WMP) is a traditional Chinese herbal formulation and widely used to treat
digestive system diseases in clinical. S‐Adenosylhomocysteine hydrolase (AHCY) can …

Cancer is a type of malignant affliction threatening human health worldwide; however, the
molecular mechanism of cancer pathogenesis remains to be elusive. The oncogenic …

Adult stem cells (ASCs) reside throughout the body and support various tissue. Owing to
their self-renewal capacity and differentiation potential, ASCs have the potential to be used …

Hepatocellular carcinoma (HCC) is the most common primary liver cancer with a high
mortality rate. It is regarded as a significant public health issue because of its complicated …