LncRNA-miRNA interaction is involved in colorectal cancer pathogenesis by modulating diverse signaling pathways

SH Alshahrani, ZSM Al-Hadeithi, SG Almalki… - … -Research and Practice, 2023 - Elsevier
LncRNAs function as molecular sponges for miRNAs to control their availability for targeting
mRNA molecules. This procedure indirectly regulates the expression of cancer-related …

Exploring the integration of nanotechnology in the development and application of biosensors for enhanced detection and monitoring of colorectal cancer

A Hajjafari, S Sadr, A Rahdar, M Bayat… - Inorganic Chemistry …, 2024 - Elsevier
As the third most severe cancer in the world, colorectal cancer (CRC) is of high concern to
global health concerns. Aging, unhealthy lifestyles, and genetic factors contribute to CRC …

Spotlight on a short-time treatment with the IL-4/IL-13 receptor blocker in patients with CRSwNP: microRNAs modulations and preliminary clinical evidence

S Mimmi, N Lombardo, D Maisano, G Piazzetta… - Genes, 2022 - mdpi.com
Already used for the treatment of some allergic and inflammatory diseases, such as asthma
or atopic dermatitis, dupilumab has also been approved as add-on therapy for patients with …

Silymarin-loaded tin (IV) nanoparticles exhibit enhanced bioavailability and antiproliferative effects on colorectal cancer cells

H Abbasinia, M Heshmati, M Yousefi… - ACS Applied Bio …, 2023 - ACS Publications
Silymarin (SM) exhibits potential therapeutic effects due to having antioxidant activity.
However, the low solubility and bioavailability of SM restrict its biological performance. To …

Colorectal cancer screening: have we addressed concerns and needs of the target population?

TN Tran, A Ferrari, S Hoeck, M Peeters… - Gastrointestinal …, 2021 - mdpi.com
Despite the recognized benefits of colorectal cancer (CRC) screening, uptake is still
suboptimal in many countries. In addressing this issue, one important element that has not …

Decoding the equine genome: lessons from ENCODE

S Peng, JL Petersen, RR Bellone, T Kalbfleisch… - Genes, 2021 - mdpi.com
The horse reference genome assemblies, EquCab2. 0 and EquCab3. 0, have enabled great
advancements in the equine genomics field, from tools to novel discoveries. However …

Analysis of miR-143, miR-1, miR-210 and let-7e expression in colorectal cancer in relation to histopathological features

H Romanowicz, P Hogendorf, A Majos, A Durczyński… - Genes, 2022 - mdpi.com
Background: MicroRNAs (miRNAs) are small RNA molecules involved in the control of the
expression of many genes and are responsible for, among other things, cell death …

Long-read RNA Sequencing Improves the Annotation of the Equine Transcriptome

S Peng, AR Dahlgren, EN Hales, AM Barber… - bioRxiv, 2022 - biorxiv.org
A high-quality reference genome assembly, a biobank of diverse equine tissues from the
Functional Annotation of the Animal Genome (FAANG) initiative, and incorporation of long …

Lactobacillus casei condition medium downregulates miR-21 relative expression in HT-29 colorectal cancer cell line

R Hosseinzadeh, A Bahadori… - FEMS Microbiology …, 2023 - academic.oup.com
Previous research has demonstrated promising outcomes regarding the advantageous
impact of probiotics in both cancer prevention and treatment. Nevertheless, the precise …

Association of GEMIN4 gene polymorphisms with the risk of colorectal cancer in the Polish population

A Cieślak, G Galita, M Mik, Ł Dziki, A Dziki… - Polish Journal of …, 2021 - ppch.pl
Aim: Gem-associated protein 4 (GEMIN4), a member of the GEMIN gene family, is a key
compound of the regulating factors responsible for miRNA biogenesis. Genetic variability …