Long-term cardiovascular consequences of fetal growth restriction: biology, clinical implications, and opportunities for prevention of adult disease

F Crispi, J Miranda, E Gratacós - American journal of obstetrics and …, 2018 - Elsevier
In the modern world, cardiovascular disease is a leading cause of death for both men and
women. Epidemiologic studies consistently have suggested an association between low …

Cardiovascular dysfunction in intrauterine growth restriction

N Amruta, HK Kandikattu, S Intapad - Current Hypertension Reports, 2022 - Springer
Abstract Purpose of Review We highlight important new findings on cardiovascular
dysfunction in intrauterine growth restriction. Recent Findings Intrauterine growth restriction …

Descriptive analysis of different phenotypes of cardiac remodeling in fetal growth restriction

M Rodríguez‐López, M Cruz‐Lemini… - … in Obstetrics & …, 2017 - Wiley Online Library
Objective To identify different cardiac phenotypes among cases of fetal growth restriction
(FGR). Methods Echocardiography was performed in 126 cases with FGR (birth weight< …

Models of Intrauterine growth restriction and fetal programming in rabbits

J Lopez‐Tello, M Arias‐Alvarez… - Molecular …, 2019 - Wiley Online Library
Intrauterine growth restriction (IUGR) affects approximately 10% of human pregnancies
globally and has immediate and life‐long consequences for offspring health. However, the …

Cardiac remodelling in a baboon model of intrauterine growth restriction mimics accelerated ageing

AH Kuo, C Li, J Li, HF Huber… - The Journal of …, 2017 - Wiley Online Library
Key points Rodent models of intrauterine growth restriction (IUGR) successfully identify
mechanisms that can lead to short‐term and long‐term detrimental cardiomyopathies but …

Whole heart detailed and quantitative anatomy, myofibre structure and vasculature from X-ray phase-contrast synchrotron radiation-based micro computed …

A Gonzalez-Tendero, C Zhang… - European Heart …, 2017 - academic.oup.com
Background While individual cardiac myocytes only have a limited ability to shorten, the
heart efficiently pumps a large volume-fraction thanks to a cell organization in a complex 3D …

Intrauterine growth restriction and later cardiovascular function

F Crispi, F Crovetto, E Gratacos - Early human development, 2018 - Elsevier
Intrauterine growth restriction is one of the most common obstetric conditions, affecting 7–
10% of fetuses. Affected fetuses are actually exposed in utero to an adverse environment …

Cardiac remodeling from the fetus to adulthood

L Youssef, R Castellani… - Journal of Clinical …, 2023 - Wiley Online Library
Prenatal cardiac remodeling refers to in utero changes in the fetal heart that occur as a
response to an adverse intrauterine environment. In this article, we will review the main …

Mitochondrial implications in human pregnancies with intrauterine growth restriction and associated cardiac remodelling

M Guitart‐Mampel, DL Juarez‐Flores… - Journal of Cellular …, 2019 - Wiley Online Library
Intrauterine growth restriction (IUGR) is an obstetric complication characterised by placental
insufficiency and secondary cardiovascular remodelling that can lead to cardiomyopathy in …

Characterizing early cardiac metabolic programming via 30% maternal nutrient reduction during fetal development in a non-human primate model

SP Pereira, MS Diniz, LC Tavares… - International Journal of …, 2023 - mdpi.com
Intra-uterine growth restriction (IUGR) is a common cause of fetal/neonatal morbidity and
mortality and is associated with increased offspring predisposition for cardiovascular …