Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria

JG Beeson, DR Drew, MJ Boyle, G Feng… - FEMS microbiology …, 2016 - academic.oup.com
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …

The cellular and molecular basis for malaria parasite invasion of the human red blood cell

AF Cowman, D Berry, J Baum - Journal of cell Biology, 2012 - rupress.org
Malaria is a major disease of humans caused by protozoan parasites from the genus
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …

Invasion of red blood cells by malaria parasites

AF Cowman, BS Crabb - Cell, 2006 - cell.com
The malaria parasite is the most important member of the Apicomplexa, a large and highly
successful phylum of intracellular parasites. Invasion of host cells allows apicomplexan …

Proteases in parasitic diseases

JH McKerrow, C Caffrey, B Kelly… - Annu. Rev. Pathol …, 2006 - annualreviews.org
Parasitic diseases represent major global health problems of immense proportion.
Schistosomiasis, malaria, leishmaniasis, Chagas disease, and African sleeping sickness …

[HTML][HTML] Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes

S Yeoh, RA O'Donnell, K Koussis, AR Dluzewski… - Cell, 2007 - cell.com
The most virulent form of malaria is caused by waves of replication of blood stages of the
protozoan pathogen Plasmodium falciparum. The parasite divides within an intraerythrocytic …

Cysteine proteases of malaria parasites

PJ Rosenthal - International journal for parasitology, 2004 - Elsevier
A number of cysteine proteases of malaria parasites have been described, and many more
putative cysteine proteases are suggested by analysis of the Plasmodium falciparum …

Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum

S Arastu-Kapur, EL Ponder, UP Fonović… - Nature chemical …, 2008 - nature.com
Newly replicated Plasmodium falciparum parasites escape from host erythrocytes through a
tightly regulated process that is mediated by multiple classes of proteolytic enzymes …

Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum

PR Sanders, PR Gilson, GT Cantin… - Journal of Biological …, 2005 - ASBMB
Glycosylphosphatidylinositol (GPI)-anchored proteins coat the surface of extracellular
Plasmodium falciparum merozoites, of which several are highly validated candidates for …

[HTML][HTML] Recent advances in recombinant protein-based malaria vaccines

SJ Draper, E Angov, T Horii, LH Miller, P Srinivasan… - Vaccine, 2015 - Elsevier
Plasmodium parasites are the causative agent of human malaria, and the development of a
highly effective vaccine against infection, disease and transmission remains a key priority. It …

Malarial proteases and host cell egress: an 'emerging'cascade

MJ Blackman - Cellular microbiology, 2008 - Wiley Online Library
Malaria is a scourge of large swathes of the globe, stressing the need for a continuing effort
to better understand the biology of its aetiological agent. Like all pathogens of the phylum …