Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …
accounting for the majority of malaria, and P. vivax being a second important cause …
The cellular and molecular basis for malaria parasite invasion of the human red blood cell
Malaria is a major disease of humans caused by protozoan parasites from the genus
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …
Invasion of red blood cells by malaria parasites
The malaria parasite is the most important member of the Apicomplexa, a large and highly
successful phylum of intracellular parasites. Invasion of host cells allows apicomplexan …
successful phylum of intracellular parasites. Invasion of host cells allows apicomplexan …
Proteases in parasitic diseases
JH McKerrow, C Caffrey, B Kelly… - Annu. Rev. Pathol …, 2006 - annualreviews.org
Parasitic diseases represent major global health problems of immense proportion.
Schistosomiasis, malaria, leishmaniasis, Chagas disease, and African sleeping sickness …
Schistosomiasis, malaria, leishmaniasis, Chagas disease, and African sleeping sickness …
[HTML][HTML] Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes
S Yeoh, RA O'Donnell, K Koussis, AR Dluzewski… - Cell, 2007 - cell.com
The most virulent form of malaria is caused by waves of replication of blood stages of the
protozoan pathogen Plasmodium falciparum. The parasite divides within an intraerythrocytic …
protozoan pathogen Plasmodium falciparum. The parasite divides within an intraerythrocytic …
Cysteine proteases of malaria parasites
PJ Rosenthal - International journal for parasitology, 2004 - Elsevier
A number of cysteine proteases of malaria parasites have been described, and many more
putative cysteine proteases are suggested by analysis of the Plasmodium falciparum …
putative cysteine proteases are suggested by analysis of the Plasmodium falciparum …
Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum
S Arastu-Kapur, EL Ponder, UP Fonović… - Nature chemical …, 2008 - nature.com
Newly replicated Plasmodium falciparum parasites escape from host erythrocytes through a
tightly regulated process that is mediated by multiple classes of proteolytic enzymes …
tightly regulated process that is mediated by multiple classes of proteolytic enzymes …
Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum
PR Sanders, PR Gilson, GT Cantin… - Journal of Biological …, 2005 - ASBMB
Glycosylphosphatidylinositol (GPI)-anchored proteins coat the surface of extracellular
Plasmodium falciparum merozoites, of which several are highly validated candidates for …
Plasmodium falciparum merozoites, of which several are highly validated candidates for …
[HTML][HTML] Recent advances in recombinant protein-based malaria vaccines
SJ Draper, E Angov, T Horii, LH Miller, P Srinivasan… - Vaccine, 2015 - Elsevier
Plasmodium parasites are the causative agent of human malaria, and the development of a
highly effective vaccine against infection, disease and transmission remains a key priority. It …
highly effective vaccine against infection, disease and transmission remains a key priority. It …
Malarial proteases and host cell egress: an 'emerging'cascade
MJ Blackman - Cellular microbiology, 2008 - Wiley Online Library
Malaria is a scourge of large swathes of the globe, stressing the need for a continuing effort
to better understand the biology of its aetiological agent. Like all pathogens of the phylum …
to better understand the biology of its aetiological agent. Like all pathogens of the phylum …