Folate titanium (IV)-chitosan nanocomposites as drug delivery system for active-targeted cancer therapy: Design, HSA/GSH binding, mechanistic, and biological …
A Alsaed, FI Elshami, MM Ibrahim, H Shereef… - Journal of Drug Delivery …, 2024 - Elsevier
Folate Ti (IV)-chitosan nanocomposite (TiFA@ CS NPs) were prepared from folate Ti (IV)-
complex (TiFA) and chitosan (CS) with optimum particle size (175±7 nm), high stability (ζ …
complex (TiFA) and chitosan (CS) with optimum particle size (175±7 nm), high stability (ζ …
Hydroxychloroquine-Loaded Chitosan Nanoparticles Induce Anticancer Activity in A549 Lung Cancer Cells: Design, BSA Binding, Molecular Docking, Mechanistic …
FI Elshami, HA Shereef, IM El-Mehasseb… - International Journal of …, 2023 - mdpi.com
The current study describes the encapsulation of hydroxychloroquine, widely used in
traditional medicine due to its diverse pharmacological and medicinal uses, in chitosan …
traditional medicine due to its diverse pharmacological and medicinal uses, in chitosan …
Steady-state and 3D fluorescence study reveals the binding of a dicoumarol analogue in subdomain IIA of human serum albumin with structural variation
Drugs exhibit pharmacological properties through their binding interactions with the target
receptors. Coumarins and dicoumarols are known to exhibit diverse pharmacological …
receptors. Coumarins and dicoumarols are known to exhibit diverse pharmacological …
Binding of dicoumarol analog with DNA and its antioxidant studies: A biophysical insight by in-vitro and in-silico approaches
DNA is the major target for a number of pharmaceutical drugs. The interaction of drug
molecules with DNA plays a major role in pharmacokinetics and pharmacodynamics. Bis …
molecules with DNA plays a major role in pharmacokinetics and pharmacodynamics. Bis …
Structure and energetics of serum protein complex of tea adulterant dye Bismarck brown Y using experimental and computational methods
Tea, a widely consumed aromatic beverage, is often adulterated with dyes such as Bismarck
brown Y (CI 21000)(BBY), Prussian blue, and Plumbago, which pose potential health risks …
brown Y (CI 21000)(BBY), Prussian blue, and Plumbago, which pose potential health risks …
Insights on the in-vitro binding characteristics of human α-1-acid glycoprotein (HAG) with JAK inhibitor ocalcitinib: Multi-spectroscopic analysis combined with …
QH Liu, Q Zhang, RJ Zhang, SL Jiang, JH Shi - Journal of Molecular …, 2024 - Elsevier
A powerful Janus kinase (JAK) inhibitor, ocalcitinib has been authorized for controlling
pruritus and atopic dermatitis from canine allergic dermatitis and many kinds of cytokines. To …
pruritus and atopic dermatitis from canine allergic dermatitis and many kinds of cytokines. To …
GSH-Responsive and Folate Receptor-Targeted pyridine bisfolate-Encapsulated chitosan Nanoparticles for Enhanced Intracellular Drug Delivery in MCF− 7 cells
FI Elshami, G Elrefaei, MM Ibrahim, I Elmehasseb… - Carbohydrate …, 2024 - Elsevier
Folic acid receptor-targeted drug delivery system is a promising candidate for tumor-targeted
delivery because its elevated expression specifically on tumor cells enables the selective …
delivery because its elevated expression specifically on tumor cells enables the selective …
Design, BSA Binding, Stopped-Flow Kinetic, Mechanistic, Molecular Docking, and Biological Evaluation of Hy-droxychloroquine-Based Chitosan Nanoparticles for …
R van Eldik, FI Elshami, HA Shereef, IM El-Mehasseb… - 2023 - preprints.org
Design, BSA Binding, Stopped- Flow Kinetic, Mechanistic, Molecular Docking, and Biological
Evaluation of Hy- droxychloroquine-Ba Page 1 Article Not peer-reviewed version Design, BSA …
Evaluation of Hy- droxychloroquine-Ba Page 1 Article Not peer-reviewed version Design, BSA …
Interactions of coreopsin with CYP3A4/CYP2D6 by multi-spectroscopy analysis and computer simulation
J Cui, M Wang, Y Du, L Li - 2023 - researchsquare.com
In this study, different spectral methods, molecular docking, dynamics simulation are applied
for revealing the binding mechanisms of coreopsin to CYP3A4/CYP2D6. Coreopsin …
for revealing the binding mechanisms of coreopsin to CYP3A4/CYP2D6. Coreopsin …