Computational screening of natural compounds as putative quorum sensing inhibitors targeting drug resistance bacteria: Molecular docking and molecular dynamics …
Quorum sensing (QS) is a bacterial communication strategy controlling cells density, biofilm
formation, virulence, sporulation, and survival. Since QS is considered a virulence factor in …
formation, virulence, sporulation, and survival. Since QS is considered a virulence factor in …
Fludarabine, a potential DNA-dependent RNA polymerase inhibitor, as a prospective drug against monkeypox virus: A computational approach
HN Altayb - Pharmaceuticals, 2022 - mdpi.com
Monkeypox is a zoonotic contagious disease that has recently re-emerged in different
countries worldwide. Due to the lack of an effective treatment that eliminates the virus, there …
countries worldwide. Due to the lack of an effective treatment that eliminates the virus, there …
[HTML][HTML] In-silico studies of glutathione peroxidase4 activators as candidate for multiple sclerosis management
AA Alameen, M Abdalla, HM Alshibl… - Journal of Saudi …, 2022 - Elsevier
Multiple sclerosis (MS) is an autoimmune and inflammatory demyelinating disease of the
central nervous system (CNS) that affects approximately 2.8 million people worldwide …
central nervous system (CNS) that affects approximately 2.8 million people worldwide …
Cheminformatics-based identification of phosphorylated RET tyrosine kinase inhibitors for human cancer
Background Rearranged during transfection (RET), an oncogenic protein, is associated with
various cancers, including non-small-cell lung cancer (NSCLC), papillary thyroid cancer …
various cancers, including non-small-cell lung cancer (NSCLC), papillary thyroid cancer …
The potential for senotherapy as a novel approach to extend life quality in veterinary medicine
Cellular senescence, a condition where cells undergo arrest and can assume an
inflammatory phenotype, has been associated with initiation and perpetuation of …
inflammatory phenotype, has been associated with initiation and perpetuation of …
Potent multi-target natural inhibitors against SARS-CoV-2 from medicinal plants of the Himalaya: a discovery from hybrid machine learning, chemoinformatics, and …
P Maiti, M Nand, S Mathpal, S Wahab… - Journal of …, 2023 - Taylor & Francis
The emergence and immune evasion ability of SARS-CoV-2 Omicron strains, mainly BA. 5.2
and BF. 7 and other variants of concern have raised global apprehensions. With this context …
and BF. 7 and other variants of concern have raised global apprehensions. With this context …
Discovery of melittin as triple-action agent: broad-spectrum antibacterial, anti-biofilm, and potential anti-quorum sensing activities
H Yang, R Ma, J Chen, Q Xie, W Luo, P Sun, Z Liu… - Molecules, 2024 - mdpi.com
The development of antibiotic-resistant microorganisms is a major global health concern.
Recently, there has been an increasing interest in antimicrobial peptides as a therapeutic …
Recently, there has been an increasing interest in antimicrobial peptides as a therapeutic …
[HTML][HTML] Insights into novel inhibitors intending HCMV protease a computational molecular modelling investigation for antiviral drug repurposing
NH Siddiquee, AA Tanni, N Sarker, SH Sourav… - Informatics in Medicine …, 2024 - Elsevier
Human cytomegalovirus (HCMV) is an important opportunistic pathogen that is the most
significant viral cause of congenital birth abnormalities and is responsible for a high …
significant viral cause of congenital birth abnormalities and is responsible for a high …
[HTML][HTML] A five-cuproptosis-related LncRNA Signature: predicting prognosis, assessing immune function & drug sensitivity in lung squamous cell carcinoma
H Zhao, L Wu, Q Liao, P Huang, R Sun, X Yang… - Journal of …, 2023 - ncbi.nlm.nih.gov
Lung squamous cell carcinoma has so far lacked effective targets for diagnosis and
treatment. In cancer research, long noncoding RNAs (LncRNAs) emerge as novel …
treatment. In cancer research, long noncoding RNAs (LncRNAs) emerge as novel …
Determination of bortezomib and dasatinib anticancer drugs in real samples using an electrochemical sensor modified with new CuFe2O4/SmVO4/ionic liquid …
A Jafari-Kashi, M Shabani-Nooshabadi… - Carbon Letters, 2024 - Springer
Bortezomib (BTZ) and dasatinib (DA) are two substantial anti-cancer agents with side effects
on the human body. In this research, we fabricated a novel electrochemical sensor modified …
on the human body. In this research, we fabricated a novel electrochemical sensor modified …