Which structure generates paradoxical (REM) sleep: The brainstem, the hypothalamus, the amygdala or the cortex?

PH Luppi, A Chancel, J Malcey, S Cabrera, P Fort… - Sleep Medicine …, 2024 - Elsevier
Paradoxical or Rapid eye movement (REM) sleep (PS) is a state characterized by REMs,
EEG activation and muscle atonia. In this review, we discuss the contribution of brainstem …

Consciousness and sleep

G Tononi, M Boly, C Cirelli - Neuron, 2024 - cell.com
Sleep is a universal, essential biological process. It is also an invaluable window on
consciousness. It tells us that consciousness can be lost but also that it can be regained, in …

40 Hz light flickering promotes sleep through cortical adenosine signaling

X Zhou, Y He, T Xu, Z Wu, W Guo, X Xu, Y Liu, Y Zhang… - Cell Research, 2024 - nature.com
Flickering light stimulation has emerged as a promising non-invasive neuromodulation
strategy to alleviate neuropsychiatric disorders. However, the lack of a neurochemical …

Auditory stimulation during REM sleep modulates REM electrophysiology and cognitive performance

M Navarrete, V Greco, M Rakowska, M Bellesi… - Communications …, 2024 - nature.com
REM sleep is critical for memory, emotion, and cognition. Manipulating brain activity during
REM could improve our understanding of its function and benefits. Earlier studies have …

Infralimbic activity during REM sleep facilitates fear extinction memory

J Hong, K Choi, MV Fuccillo, S Chung, F Weber - Current Biology, 2024 - cell.com
Rapid eye movement (REM) sleep is known to facilitate fear extinction and play a protective
role against fearful memories. 1, 2 Consequently, disruption of REM sleep after a traumatic …

Crosstalk between the subiculum and sleep–wake regulation: A review

S Rahimi, L Joyce, T Fenzl… - Journal of Sleep …, 2024 - Wiley Online Library
The circuitry underlying the initiation, maintenance, and coordination of wakefulness, rapid
eye movement sleep, and non‐rapid eye movement sleep is not thoroughly understood …

Generalized sleep decoding with basal ganglia signals in multiple movement disorders

Z Yin, H Yu, T Yuan, C Smyth, MF Anjum, G Zhu… - npj Digital …, 2024 - nature.com
Sleep disturbances profoundly affect the quality of life in individuals with neurological
disorders. Closed-loop deep brain stimulation (DBS) holds promise for alleviating sleep …

Sleepiness and the transition from wakefulness to sleep

T Andrillon, J Taillard, M Strauss - Neurophysiologie Clinique, 2024 - Elsevier
The transition from wakefulness to sleep is a progressive process that is reflected in the
gradual loss of responsiveness, an alteration of cognitive functions, and a drastic shift in …

Aberrant individual large-scale functional network connectivity and topology in chronic insomnia disorder with and without depression

M Chen, H Shao, L Wang, J Ma, J Chen, J Li… - Progress in Neuro …, 2024 - Elsevier
Insomnia is increasingly prevalent with significant associations with depression. Delineating
specific neural circuits for chronic insomnia disorder (CID) with and without depressive …

LT-102, an AMPA receptor potentiator, alleviates depression-like behavior and synaptic plasticity impairments in prefrontal cortex induced by sleep deprivation

Y Zheng, X Yu, L Wei, Q Chen, Y Xu, P Ni… - Journal of Affective …, 2024 - Elsevier
Background Sleep loss is closely related to the onset and development of depression, and
the mechanisms involved may include impaired synaptic plasticity. Considering the …