Leishmaniasis, presenting the highest number of cases worldwide is one of the most serious
Neglected Tropical Diseases (NTDs). Clinical manifestations are intrinsically related to the …

Silver is arguably the best plasmonic material in terms of optical performance. However,
wide application of Ag and Ag-containing nanoparticles is usually hindered by two major …

Two β-carboline compounds, 8i and 6d, demonstrated in vitro antileishmanial activity
against Leishmania (L.) amazonensis promastigotes similar to that of miltefosine (MIL) …

A novel chalcone derivative, LQFM064, demonstrated antileishmanial activity against
Leishmania (L.) amazonensis, with an IC 50 value of~ 10 μM for the promastigote form …

The basic aim of the study was to develop and evaluate the triple drug loaded cationic nano-
vesicles (cNVs), where miltefosine was used as a replacement of surfactant (apart from its …

Objetivo: Descrever o arsenal terapêutico utilizado para o tratamento da Leishmaniose
Cutânea (LC), revisando a literatura científica que tenha abordagem nos aspetos …

The isoxazole core has been identified as an essential privileged structure in discovering
new and potent leishmanicidal agents. Thus, the present study reports the in vitro activity of …

Novel chalcone-like compounds, LQFM332 (4), LQFM333 (5), and LQFM341 (6), were
synthesized and their activity against Leishmania (L.) amazonensis was evaluated and …

Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to study the
interactions of amphotericin B (AmB) with the plasma membrane of Leishmania …

hydroxy-2-nonenal (HNE) is a reactive aldehyde produced by cells under conditions of
oxidative stress, which has been shown to react with proteins and …