[HTML][HTML] The mesopontine tegmentum in reward and aversion: from cellular heterogeneity to behaviour

R Bastos-Gonçalves, B Coimbra… - … & Biobehavioral Reviews, 2024 - Elsevier
The mesopontine tegmentum, comprising the pedunculopontine tegmentum (PPN) and the
laterodorsal tegmentum (LDT), is intricately connected to various regions of the basal …

A novel perspective on the role of nucleus accumbens neurons in encoding associative learning

AV Domingues, AJ Rodrigues, C Soares‐Cunha - FEBS letters, 2023 - Wiley Online Library
The nucleus accumbens (NAc) has been considered a key brain region for encoding
reward/aversion and cue–outcome associations. These processes are encoded by medium …

A putative loop connection between VTA dopamine neurons and nucleus accumbens encodes positive valence to compensate for hunger

X Cui, Q Tong, H Xu, C Xie, L Xiao - Progress in Neurobiology, 2023 - Elsevier
Dopamine (DA) signal play pivotal roles in regulating motivated behaviors, including feeding
behavior, but the role of midbrain DA neurons in modulating food intake and neural circuitry …

[HTML][HTML] Molecular and circuit determinants in the globus pallidus mediating control of cocaine-induced behavioral plasticity

G Tian, K Bartas, M Hui, L Chen, JJ Vasquez, G Azouz… - Neuron, 2024 - cell.com
The globus pallidus externus (GPe) is a central component of the basal ganglia circuit that
acts as a gatekeeper of cocaine-induced behavioral plasticity. However, the molecular and …

Nucleus accumbens neurons dynamically respond to appetitive and aversive associative learning

C Deseyve, AV Domingues… - Journal of …, 2024 - Wiley Online Library
To survive, individuals must learn to associate cues in the environment with emotionally
relevant outcomes. This association is partially mediated by the nucleus accumbens (NAc) …

[HTML][HTML] Dissociable encoding of motivated behavior by parallel thalamo-striatal projections

S Beas, I Khan, C Gao, G Loewinger, E Macdonald… - Current Biology, 2024 - cell.com
The successful pursuit of goals requires the coordinated execution and termination of
actions that lead to positive outcomes. This process relies on motivational states that are …

Comparison of dopamine release and uptake parameters across sex, species and striatal subregions

LB Kuiper, MH Dawes, AM West… - European Journal of …, 2024 - Wiley Online Library
For over four decades, fast‐scan cyclic voltammetry (FSCV) has been used to selectively
measure neurotransmitters such as dopamine (DA) with high spatial and temporal …

Distinct Action Signals by Subregions in the Nucleus Accumbens during STOP–Change Performance

SE Ashton, P Sharalla, N Kang, AT Brockett… - Journal of …, 2024 - jneurosci.org
The nucleus accumbens (NAc) is thought to contribute to motivated behavior by signaling
the value of reward-predicting cues and the delivery of anticipated reward. The NAc is …

Tetherless Optical Neuromodulation: Wavelength from Orange-red to Mid-infrared

C Sun, Q Fan, R Xie, C Luo, B Hu, Q Wang - Neuroscience Bulletin, 2024 - Springer
Optogenetics, a technique that employs light for neuromodulation, has revolutionized the
study of neural mechanisms and the treatment of neurological disorders due to its high …

[HTML][HTML] Distinct circuits and molecular targets of the paraventricular hypothalamus decode visceral and somatic pain

YC Li, FC Zhang, D Li, RX Weng, Y Yu, R Gao, GY Xu - Neuron, 2024 - cell.com
Visceral and somatic pain serve as protective mechanisms against external threats.
Accumulated evidence has confirmed that the paraventricular hypothalamus (PVH) plays an …