The thalassemias are among the most common inherited diseases worldwide, affecting
individuals originating from the Mediterranean area, Middle East, Transcaucasia, Central …

BACKGROUND Cell-free fetal nucleic acids (cffNA) can be detected in the maternal
circulation during pregnancy, potentially offering an excellent method for early non-invasive …

Clinical advances enable the prenatal diagnosis of genetic diseases that are candidates for
gene and enzyme therapies such as messenger RNA (mRNA)–mediated protein …

We directly sequenced cell-free DNA with high-throughput shotgun sequencing technology
from plasma of pregnant women, obtaining, on average, 5 million sequence tags per patient …

We have developed a real-time quantitative PCR assay to measure the concentration of fetal
DNA in maternal plasma and serum. Our results show that fetal DNA is present in high …

Background Screening for aneuploid pregnancies is routinely performed after 15 weeks of
gestation and has a sensitivity of approximately 65 percent, with a false positive rate of 5 …

Current methods for prenatal diagnosis of chromosomal aneuploidies involve the invasive
sampling of fetal materials using procedures such as amniocentesis or chorionic villus …

The invention relates to a detection method performed on a maternal serum or plasma
sample from a pregnant female, which method comprises detecting the presence of a …

Background Fetal cells can be found in the maternal circulation in most pregnancies. Fetal
progenitor cells have been found to persist in the circulation of women many years after …

First worldwide family litigation filed litigation https://patents. darts-ip. com/? family=
46322521&utm_source= google_patent&utm_medium= platform_link&utm_campaign …