Some prospective alternatives for treating pain: the endocannabinoid system and its putative receptors GPR18 and GPR55
R Guerrero-Alba, P Barragán-Iglesias… - Frontiers in …, 2019 - frontiersin.org
Background: Marijuana extracts (cannabinoids) have been used for several millennia for
pain treatment. Regarding the site of action, cannabinoids are highly promiscuous …
pain treatment. Regarding the site of action, cannabinoids are highly promiscuous …
Novel bioactive glycerol-based lysophospholipids: new data–new insight into their function
A Grzelczyk, E Gendaszewska-Darmach - Biochimie, 2013 - Elsevier
Based on the results of research conducted over last two decades, lysophospholipids (LPLs)
were observed to be not only structural components of cellular membranes but also …
were observed to be not only structural components of cellular membranes but also …
Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55
CM Henstridge, NAB Balenga, J Kargl… - Molecular …, 2011 - academic.oup.com
Emerging data suggest that off-target cannabinoid effects may be mediated via novel seven-
transmembrane spanning/G protein-coupled receptors. Due to its cannabinoid sensitivity …
transmembrane spanning/G protein-coupled receptors. Due to its cannabinoid sensitivity …
Lysophosphatidylinositols, from cell membrane constituents to GPR55 ligands
M Alhouayek, J Masquelier, GG Muccioli - Trends in pharmacological …, 2018 - cell.com
Lysophosphatidylinositols (LPIs) are membrane constituents that alter the properties of said
membranes. However, recent data showing that the once orphan receptor, GPR55, can act …
membranes. However, recent data showing that the once orphan receptor, GPR55, can act …
Lysophosphatidylinositol signalling: new wine from an old bottle
R Piñeiro, M Falasca - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2012 - Elsevier
Lysophosphatidylinositol (LPI) is a bioactive lipid generated by phospholipase A2 which is
believed to play an important role in several diseases. Indeed LPI can affect various …
believed to play an important role in several diseases. Indeed LPI can affect various …
[HTML][HTML] Lysolecithin as feed additive enhances collagen expression and villus length in the jejunum of broiler chickens
Adding lysolecithin to feed has reportedly improved the performance of broiler chickens.
Lysolecithin is generated by phospholipase catalyzed hydrolysis of lecithin. The enzymatic …
Lysolecithin is generated by phospholipase catalyzed hydrolysis of lecithin. The enzymatic …
[HTML][HTML] Lysophosphatidylinositol signalling and metabolic diseases
Metabolism is a chemical process used by cells to transform food-derived nutrients, such as
proteins, carbohydrates and fats, into chemical and thermal energy. Whenever an alteration …
proteins, carbohydrates and fats, into chemical and thermal energy. Whenever an alteration …
GPR55‐dependent stimulation of insulin secretion from isolated mouse and human islets of L angerhans
B Liu, S Song, I Ruz-Maldonado… - Diabetes, Obesity …, 2016 - Wiley Online Library
Aims The novel cannabinoid receptor GPR55 is expressed by rodent islets and it has been
implicated in β‐cell function in response to a range of ligands. This study evaluated the …
implicated in β‐cell function in response to a range of ligands. This study evaluated the …
GPR55: from orphan to metabolic regulator?
B Liu, S Song, PM Jones, SJ Persaud - Pharmacology & therapeutics, 2015 - Elsevier
GPR55 belongs to the class A family of G-protein coupled receptor (GPCRs) and its activity
is regulated by a range of synthetic and endogenous cannabinoids, and by lipid-derived …
is regulated by a range of synthetic and endogenous cannabinoids, and by lipid-derived …
[图书][B] The endocannabinoidome: the world of endocannabinoids and related mediators
V Di Marzo, J Wang - 2014 - books.google.com
The Endocannabinoidome: The World of Endocannabinoids and Related Mediators is
dedicated to the latest research and studies on endocannabinoids and cannabinoid …
dedicated to the latest research and studies on endocannabinoids and cannabinoid …