The role of hexokinases in epigenetic regulation: altered hexokinase expression and chromatin stability in yeast

S Karri, Q Dickinson, J Jia, Y Yang, H Gan… - Epigenetics & …, 2024 - Springer
Abstract Background Human hexokinase 2 (HK2) plays an important role in regulating
Warburg effect, which metabolizes glucose to lactate acid even in the presence of ample …

Molecular mechanisms governing Hexokinase 2 nuclear shuttling and resistance to 2-deoxyglucose

MA Lesko - 2024 - d-scholarship.pitt.edu
Hexokinases represent the gateway enzyme of glucose metabolism by regulating cellular
glucose uptake and glycolytic rate. Interestingly, some mammalian hexokinase isoforms …