Ultrafast water permeation through nanochannels with a densely fluorous interior surface
Ultrafast water permeation in aquaporins is promoted by their hydrophobic interior surface.
Polytetrafluoroethylene has a dense fluorine surface, leading to its strong water repellence …
Polytetrafluoroethylene has a dense fluorine surface, leading to its strong water repellence …
Guanidinium-based “molecular glues” for modulation of biomolecular functions
Molecular adhesion based on multivalent interactions plays essential roles in various
biological processes. Hence,“molecular glues” that can adhere to biomolecules may …
biological processes. Hence,“molecular glues” that can adhere to biomolecules may …
Cellular uptake of substrate-initiated cell-penetrating poly (disulfide) s
G Gasparini, EK Bang, G Molinard… - Journal of the …, 2014 - ACS Publications
Substrate-initiated, self-inactivating, cell-penetrating poly (disulfide) s (siCPDs) are
introduced as general transporters for the covalent delivery of unmodified substrates of free …
introduced as general transporters for the covalent delivery of unmodified substrates of free …
Light-and electric-field-controlled wetting behavior in nanochannels for regulating nanoconfined mass transport
Water wetting behavior in nanoconfined environments plays an important role in mass
transport and signal transmission of organisms. It is valuable and challenging to investigate …
transport and signal transmission of organisms. It is valuable and challenging to investigate …
Linear versus dendritic molecular binders for hydrogel network formation with clay nanosheets: studies with ABA triblock copolyethers carrying guanidinium ion …
ABA-triblock copolyethers 1a–1c as linear polymeric binders, in combination with clay
nanosheets (CNSs), afford high-water-content moldable supramolecular hydrogels with …
nanosheets (CNSs), afford high-water-content moldable supramolecular hydrogels with …
Light-responsive nanochannels based on the supramolecular host–guest system
J Quan, Y Guo, J Ma, D Long, J Wang, L Zhang… - Frontiers in …, 2022 - frontiersin.org
The light-responsive nanochannel of rhodopsin gained wider research interest from its
crucial roles in light-induced biological functions, such as visual signal transduction and …
crucial roles in light-induced biological functions, such as visual signal transduction and …
Reductively cleavable nanocaplets for siRNA delivery by template-assisted oxidative polymerization
A series of water-soluble telechelic dithiol monomers bearing multiple guanidinium ion
(Gu+) units in their main chains were synthesized for packaging siRNA by template-assisted …
(Gu+) units in their main chains were synthesized for packaging siRNA by template-assisted …
Transferrin-appended nanocaplet for transcellular siRNA delivery into deep tissues
Transferrin (Tf) is known to induce transcytosis, which is a consecutive endocytosis/
exocytosis event. We developed a Tf-appended nanocaplet (TfNC⊃ siRNA) for the purpose …
exocytosis event. We developed a Tf-appended nanocaplet (TfNC⊃ siRNA) for the purpose …
Intracellular photoactivation of caspase-3 by molecular glues for spatiotemporal apoptosis induction
NB Hentzen, R Mogaki, S Otake… - Journal of the American …, 2020 - ACS Publications
Caspase-3 (Casp-3) is an enzyme that efficiently induces apoptosis, a form of programmed
cell death. We report a dendritic molecular glue PCGlue that enables intracellular delivery of …
cell death. We report a dendritic molecular glue PCGlue that enables intracellular delivery of …
Adhesive photoswitch: selective photochemical modulation of enzymes under physiological conditions
We developed a water-soluble adhesive photoswitch (Glue n-Azo-SA, average n= 5) that
selectively binds to a target enzyme and photochemically modulates its enzymatic activity …
selectively binds to a target enzyme and photochemically modulates its enzymatic activity …