• An overview of the current understanding of bleeding and thrombosis in cirrhosis.• An
evidence-based justification for bleeding risk assessment in patients with cirrhosis before …

Patients with cirrhosis develop complex alterations in primary hemostasis that include both
hypocoagulable and hypercoagulable features. This includes thrombocytopenia, multiple …

The prevention and management of bleeding and thrombosis in patients with cirrhosis
poses several difficult clinical questions. These Clinical Practice Guidelines have been …

The demand for platelets in England was stable at around 220,000 adult therapeutic doses
(ATD) per year until 2007/8 at which point demand has increased year on year to 275,000 …

Liver disease is the twelfth commonest cause of mortality in adults in the United States,
resulting in 34,000 deaths annually from cirrhosis. 7 In addition, the rising incidence of HCC …

Background Post‐extraction bleeding (PEB) is a recognised, frequently encountered
complication in dental practice, which is defined as bleeding that continues beyond 8 to 12 …

Objective Impaired health conditions and related lack of adequate host healing are among
the most important conditions that account for dental implant failure. Today clinicians face an …

From its inception the success of liver transplantation has been associated with massive
blood loss. Massive transfusion is classically defined as> 10 units of red blood cells within …

Background Gaps of knowledge still exist about the potential association between severe
thrombocytopenia and increased risk of procedure‐associated bleeding in patients with liver …

The liver plays a key role in both protein biosynthesis and lipid metabolism. As a result,
hepatic synthetic dysfunction can have adverse effects on both cellular and soluble …