Mitochondrial dynamics in neurodegenerative diseases: unraveling the role of fusion and fission processes

H Grel, D Woznica, K Ratajczak, E Kalwarczyk… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases (NDs) are a diverse group of disorders characterized by the
progressive degeneration and death of neurons, leading to a range of neurological …

Glass capillary-based nanopores for single molecule/single cell detection

X Guan, H Li, L Chen, G Qi, Y Jin - ACS sensors, 2023 - ACS Publications
A glass capillary-based nanopore (G-nanopore), due to its tapered tip, easy tunability in
orifice size, and especially its flexible surface modifications that can be tailored to effectively …

TME-triggered MnSiO3@ Met@ GOx nanosystem for ATP dual-inhibited starvation/chemodynamic synergistic therapy

J Zhang, C Liang, Z Wei, W Yang, W Ge, X Qu, W Si… - Biomaterials, 2022 - Elsevier
Adenosine triphosphate (ATP) is an essential substance for maintaining tumor cell survival
and proliferation. Inhibiting the ATP-producing pathways has emerged as a promising …

Universal near-infrared fluorescent nanoprobes for detection and real-time imaging of ATP in real food samples, living cells, and bacteria

N Ding, M Qin, Y Sun, S Qi, X Dong… - Journal of Agricultural …, 2023 - ACS Publications
Adenosine triphosphate (ATP), an essential metabolite for active microorganisms to
maintain life activities, has been widely regarded as a marker of cell activity and an indicator …

Drug‐Loaded Nanogel for Efficient Orchestration of Cell Death Pathways by Intramitochondrial Disulfide Polymerization

ES Choi, S Kim, D Kim, E Choi, JH Ryu - Small, 2024 - Wiley Online Library
Chemotherapy using a nanoscaled drug delivery system is an effective cancer therapy, but
its high drug concentration often causes drug resistance in cancer cells and normal cell …

Dual-emission red carbon dots for ATP real-time monitoring and quantification to reveal drug and cancer effects on lysosomes

J Hu, T Wang, J Xu, J Hai, Y Ji, R Li - Talanta, 2024 - Elsevier
Monitoring and quantifying ATP levels in vivo is essential to understanding its role as a
signaling molecule in tumor progression and therapy. Nevertheless, the real-time monitoring …

[HTML][HTML] Self-assembly inside cellular organelles: Aspects of functions and various strategies for cancer therapy

S Kim, H Choi, S Jin, S Son, Y Lee, K Kim, JH Ryu - Giant, 2023 - Elsevier
Self-assembly generates three-dimensional architectures through the non-covalent
interactions of building blocks of various sizes, ranging from nanometers to micrometers …

Synthetic Nanoassemblies for Regulating Organelles: From Molecular Design to Precision Therapeutics

Y Guo, P Li, X Guo, C Yao, D Yang - ACS nano, 2024 - ACS Publications
Each organelle referring to a complex multiorder architecture executes respective biological
processes via its distinct spatial organization and internal microenvironment. As the …

Synthesis of a metal–organic framework Cu-Mi-UiO-66-based fluorescent nanoprobe for the simultaneous sensing and intracellular imaging of GSH and ATP

Y Liu, S Xia, M Xiao, M Yang, M Yang, C Yi - Nanoscale, 2024 - pubs.rsc.org
This study reports a fluorescent nanoprobe operated in fluorescence turn-on mode for
simultaneously sensing and imaging intracellular GSH and ATP. By using maleimide …

Folic Acid-Functionalized β-Cyclodextrin for Delivery of Organelle-Targeted Peptide Chemotherapeutics in Cancer

HW Ok, S Jin, G Park, B Jana, JH Ryu - Molecular Pharmaceutics, 2024 - ACS Publications
Recent emphasis on the design of drug delivery systems typically involves the effective
transport of a pharmaceutical substance to the disease site with the desired therapeutic …