[HTML][HTML] PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up
MC Operti, A Bernhardt, S Grimm, A Engel… - International Journal of …, 2021 - Elsevier
Nanomedicines based on poly (lactic-co-glycolic acid)(PLGA) carriers offer tremendous
opportunities for biomedical research. Although several PLGA-based systems have already …
opportunities for biomedical research. Although several PLGA-based systems have already …
Topical drug delivery: History, percutaneous absorption, and product development
Topical products, widely used to manage skin conditions, have evolved from simple potions
to sophisticated delivery systems. Their development has been facilitated by advances in …
to sophisticated delivery systems. Their development has been facilitated by advances in …
Assessing and predicting physical stability of emulsion-based topical semisolid products: a review
AZM Badruddoza, T Yeoh, JC Shah, T Walsh - Journal of Pharmaceutical …, 2023 - Elsevier
The emulsion-based topical semisolid dosage forms present a high degree of complexity
due to their microstructures which is apparent from their compositions comprising at least …
due to their microstructures which is apparent from their compositions comprising at least …
Rheology by design: A regulatory tutorial for analytical method validation
The increasing demand for product and process understanding as an active pursuit in the
quality guideline Q8 and, more recently, on the draft guideline on quality and equivalence of …
quality guideline Q8 and, more recently, on the draft guideline on quality and equivalence of …
Transdermal Drug Delivery Systems (TDDS): recent advances and failure modes
Transdermal drug delivery systems (TDDS), commonly refered to as" patches", present a
nonintrusive technique to provide medication without the need for invasive procedures …
nonintrusive technique to provide medication without the need for invasive procedures …
Viscoelastic and deformation characteristics of structurally different commercial topical systems
Rheological characteristics and shear response have potential implication in defining the
pharmaceutical equivalence, therapeutic equivalence, and perceptive equivalence of …
pharmaceutical equivalence, therapeutic equivalence, and perceptive equivalence of …
Topical caffeine-loaded nanostructured lipid carriers for enhanced treatment of cellulite: A 32 full factorial design optimization and in vivo evaluation in rats
The goal of this study was the development and evaluation of semisolid caffeine (CAF)
loaded nanostructured lipid carriers (NLCs) for topical treatment of cellulite. CAF-loaded …
loaded nanostructured lipid carriers (NLCs) for topical treatment of cellulite. CAF-loaded …
The implications of regulatory framework for topical semisolid drug products: From critical quality and performance attributes towards establishing bioequivalence
T Ilić, I Pantelić, S Savić - Pharmaceutics, 2021 - mdpi.com
Due to complex interdependent relationships affecting their microstructure, topical semisolid
drug formulations face unique obstacles to the development of generics compared to other …
drug formulations face unique obstacles to the development of generics compared to other …
Polyaphron dispersion technology, a novel topical formulation and delivery system combining drug penetration, local tolerability and convenience of application
M Praestegaard, F Steele, N Crutchley - Dermatology and Therapy, 2022 - Springer
Topical formulation and delivery technologies for pharmaceutical application should
simultaneously address efficacy, safety and convenience of therapy. This has historically …
simultaneously address efficacy, safety and convenience of therapy. This has historically …
Rational design of topical semi-solid dosage forms-how far are we?
ME Herbig, DH Evers, S Gorissen, M Köllmer - Pharmaceutics, 2023 - mdpi.com
Specific aspects of semi-solid dosage forms for topical application include the nature of the
barrier to be overcome, aspects of susceptibility to physical and chemical instability, and a …
barrier to be overcome, aspects of susceptibility to physical and chemical instability, and a …