Nanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted
cancer therapy due to their ability to overcome many of the key challenges currently being …

Despite significant advancements made in the treatment of cancer during the past several
decades, it remains one of the leading causes of death worldwide killing approximately 9.6 …

Imprecise targeting of chemotherapeutic drugs often leads to severe toxicity during breast
cancer therapy. To address this issue, we have devised a strategy to load dacarbazine (DC) …

Genistein is an isoflavonoid present in high quantities in soybeans. Possessing a wide
range of bioactives, it is being studied extensively for its tumoricidal effects. Investigations …

A two-tier approach has been proposed for targeted and synergistic combination therapy
against metastatic breast cancer. First, it comprises the development of a paclitaxel (PX) …

Cancer is one of the leading causes of death worldwide, so pursuing effective and safe
therapeutics for cancer is a key research objective nowadays. Doxorubicin (DOX) is one of …

The most prevalent clinical option for treating cancer is combination chemotherapy. In
combination therapy, assessment and optimization for obtaining a synergistic ratio could be …

Breast cancer (BC) is one of the most common malignancies in women. Although
widespread successful synthetic drugs are available, natural compounds can also be …

In the current study, we aimed to develop lyotropic crystalline nanoconstructs (LCNs) based
on poly (l-glutamic acid)(PLG) with a two-tier strategy. The first objective was to confer pH …

In recent years, Onco-immunotherapies (OIMTs) have been shown to be a potential therapy
option for cancer. Several immunotherapies have received regulatory approval, while many …