[HTML][HTML] The glycosylation in SARS-CoV-2 and its receptor ACE2
Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …
Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment
S Boopathi, AB Poma, P Kolandaivel - Journal of Biomolecular …, 2021 - Taylor & Francis
In the past two decades, the world has faced several infectious disease outbreaks. Ebola,
Influenza A (H1N1), SARS, MERS, and Zika virus have had a massive global impact in terms …
Influenza A (H1N1), SARS, MERS, and Zika virus have had a massive global impact in terms …
[HTML][HTML] Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers
VS Mandala, MJ McKay, AA Shcherbakov… - Nature structural & …, 2020 - nature.com
An essential protein of the SARS-CoV-2 virus, the envelope protein E, forms a
homopentameric cation channel that is important for virus pathogenicity. Here we report a …
homopentameric cation channel that is important for virus pathogenicity. Here we report a …
[HTML][HTML] Coronavirus envelope protein: current knowledge
D Schoeman, BC Fielding - Virology journal, 2019 - Springer
Abstract Background Coronaviruses (CoVs) primarily cause enzootic infections in birds and
mammals but, in the last few decades, have shown to be capable of infecting humans as …
mammals but, in the last few decades, have shown to be capable of infecting humans as …
Recent discovery and development of inhibitors targeting coronaviruses
T Pillaiyar, S Meenakshisundaram, M Manickam - Drug discovery today, 2020 - Elsevier
Human coronaviruses (CoVs) are enveloped viruses with a positive-sense single-stranded
RNA genome. Currently, six human CoVs have been reported including human coronavirus …
RNA genome. Currently, six human CoVs have been reported including human coronavirus …
[HTML][HTML] Coronaviruses—drug discovery and therapeutic options
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …
[HTML][HTML] Novel coronavirus-induced NLRP3 inflammasome activation: a potential drug target in the treatment of COVID-19
A Shah - Frontiers in immunology, 2020 - frontiersin.org
Novel coronaviruses (nCoVs) encode ion-channel proteins called viroporins such as protein
E, open reading frame 3a (ORF3a) and ORF8a. These viroporins, via mechanisms such as …
E, open reading frame 3a (ORF3a) and ORF8a. These viroporins, via mechanisms such as …
Membrane binding proteins of coronaviruses
EA J Alsaadi, IM Jones - Future Virology, 2019 - Future Medicine
Coronaviruses (CoVs) infect many species causing a variety of diseases with a range of
severities. Their members include zoonotic viruses with pandemic potential where …
severities. Their members include zoonotic viruses with pandemic potential where …
[HTML][HTML] The SARS-coronavirus infection cycle: a survey of viral membrane proteins, their functional interactions and pathogenesis
NA Wong, MH Saier Jr - International journal of molecular sciences, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel epidemic
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
Characterization of the SARS‐CoV‐2 E protein: sequence, structure, viroporin, and inhibitors
Y Cao, R Yang, I Lee, W Zhang, J Sun, W Wang… - Protein …, 2021 - Wiley Online Library
The COVID‐19 epidemic is one of the most influential epidemics in history. Understanding
the impact of coronaviruses (CoVs) on host cells is very important for disease treatment. The …
the impact of coronaviruses (CoVs) on host cells is very important for disease treatment. The …