Macrophages can be affected by a variety of factors to change their phenotype and thus
affect their function. Activated macrophages are usually divided into two categories, M1-like …

Macrophage scavenger receptor 1 (MSR1), also named CD204, holds key inflammatory
roles in multiple pathophysiologic processes. Present primarily on the surface of various …

Simple Summary Prostate cancer is the most common malignancy in men, with a high
mortality rate when disease progresses to metastasis and therapeutic resistance. Evidence …

JCI - Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis Go
to JCI Insight About Editors Consulting Editors For authors Publication ethics Alerts Advertising …

Interleukin (IL)-4 and IL-13 are known as pleiotropic Th2 cytokines with a wide range of
biological properties and functions especially in immune responses. In addition, increasing …

We are living through an unprecedented accumulation of data on gene expression by
macrophages, reflecting their origin, distribution, and localization within all organs of the …

Background and Purpose: Atherosclerosis is an underlying cause of coronary heart disease.
Foam cell, a hallmark of atherosclerosis, is prominently derived from monocyte-differentiated …

It is often difficult to regain neurological function following spinal cord injury (SCI).
Neuroinflammation is thought to be responsible for this failure. Regulating the inflammatory …

Background & Aims Obesity-associated inflammation is a key player in the pathogenesis of
non-alcoholic fatty liver disease (NAFLD). However, the role of macrophage scavenger …

Rationale: Doxorubicin-induced cardiomyopathy (DiCM) is a primary cause of heart failure
and mortality in cancer patients, in which macrophage-orchestrated inflammation serves as …