Deep learning in ophthalmology: the technical and clinical considerations

DSW Ting, L Peng, AV Varadarajan, PA Keane… - Progress in retinal and …, 2019 - Elsevier
The advent of computer graphic processing units, improvement in mathematical models and
availability of big data has allowed artificial intelligence (AI) using machine learning (ML) …

Artificial intelligence in OCT angiography

TT Hormel, TS Hwang, ST Bailey, DJ Wilson… - Progress in Retinal and …, 2021 - Elsevier
Optical coherence tomographic angiography (OCTA) is a non-invasive imaging modality that
provides three-dimensional, information-rich vascular images. With numerous studies …

Artificial intelligence in retinal disease: clinical application, challenges, and future directions

M Daich Varela, S Sen, TAC De Guimaraes… - Graefe's Archive for …, 2023 - Springer
Retinal diseases are a leading cause of blindness in developed countries, accounting for
the largest share of visually impaired children, working-age adults (inherited retinal …

MEDnet, a neural network for automated detection of avascular area in OCT angiography

Y Guo, A Camino, J Wang, D Huang… - Biomedical optics …, 2018 - opg.optica.org
Screening and assessing diabetic retinopathy (DR) are essential for reducing morbidity
associated with diabetes. Macular ischemia is known to correlate with the severity of …

[HTML][HTML] Artificial intelligence and optical coherence tomography imaging

R Kapoor, BT Whigham, LA Al-Aswad - Asia-Pacific Journal of …, 2019 - Elsevier
This review article aimed to highlight the application and use of artificial intelligence (AI) in
optical coherence tomography (OCT) imaging in ophthalmology. Artificial intelligence …

Real-time retinal layer segmentation of OCT volumes with GPU accelerated inferencing using a compressed, low-latency neural network

S Borkovkina, A Camino, W Janpongsri… - Biomedical optics …, 2020 - opg.optica.org
Segmentation of retinal layers in optical coherence tomography (OCT) is an essential step in
OCT image analysis for screening, diagnosis, and assessment of retinal disease …

Choroideremia: from genetic and clinical phenotyping to gene therapy and future treatments

A Mitsios, AM Dubis… - Therapeutic advances in …, 2018 - journals.sagepub.com
Choroideremia is an X-linked inherited chorioretinal dystrophy leading to blindness by late
adulthood. Choroideremia is caused by mutations in the CHM gene which encodes Rab …

Prediction of visual impairment in retinitis pigmentosa using deep learning and multimodal fundus images

TYA Liu, C Ling, L Hahn, CK Jones… - British Journal of …, 2023 - bjo.bmj.com
Background The efficiency of clinical trials for retinitis pigmentosa (RP) treatment is limited
by the screening burden and lack of reliable surrogate markers for functional end points …

A systematic review of artificial intelligence applications used for inherited retinal disease management

M Esengoenuel, A Marta, J Beirao, IM Pires, A Cunha - Medicina, 2022 - mdpi.com
Nowadays, Artificial Intelligence (AI) and its subfields, Machine Learning (ML) and Deep
Learning (DL), are used for a variety of medical applications. It can help clinicians track the …

Beyond performance metrics: automatic deep learning retinal OCT analysis reproduces clinical trial outcome

J Loo, TE Clemons, EY Chew, M Friedlander, GJ Jaffe… - Ophthalmology, 2020 - Elsevier
Purpose To validate the efficacy of a fully automatic, deep learning–based segmentation
algorithm beyond conventional performance metrics by measuring the primary outcome of a …