In the brain, mitochondrial metabolism has been largely associated with energy production,
and its dysfunction is linked to neuronal cell loss. However, the functional role of …

Adrenoleukodystrophy (ALD) is a rare X‐linked disease caused by a mutation of the
peroxisomal ABCD1 gene. This review summarizes our current understanding of the …

Abstract X-linked adrenoleukodystrophy (X-ALD) is the most common peroxisomal disorder.
The disease is caused by mutations in the ABCD1 gene that encodes the peroxisomal …

The vital importance of plant surface wax in protecting tissue from environmental stresses is
reflected in the huge commitment of epidermal cells to cuticle formation. During cuticle …

The cuticle covers the aerial portions of land plants. It consists of amorphous intracuticular
wax embedded in cutin polymer, and epicuticular wax crystalloids that coat the outer plant …

X-Linked adrenoleukodystrophy (ALD) is a peroxisomal metabolic disorder with a highly
complex clinical presentation. ALD is caused by mutations in the ABCD1 gene, which leads …

Until the advent of MR imaging, knowledge of the structure of myelin and the process of
myelination were of little importance to the neuroradiologist. Other than some mild changes …

Multiple Sclerosis (MS) is an immune-mediated neurological disorder, characterized by
central nervous system (CNS) inflammation, oligodendrocyte loss, demyelination, and …

X-linked adrenoleukodystrophy (X-ALD) is the most frequent peroxisomal disease. The two
main clinical phenotypes of X-ALD are adrenomyeloneuropathy (AMN) and inflammatory …

Oxygen (O2) is an essential substrate in cellular metabolism, bioenergetics, and signaling
and as such linked to the survival and normal function of all metazoans. Low O2 tension …