Vascular regeneration in peripheral artery disease

JP Cooke, S Meng - Arteriosclerosis, thrombosis, and vascular …, 2020 - Am Heart Assoc
Peripheral artery disease is a common disorder and a major cause of morbidity and mortality
worldwide. Therapy is directed at reducing the risk of major adverse cardiovascular events …

Skeletal muscle as an experimental model of choice to study tissue aging and rejuvenation

J Etienne, C Liu, CM Skinner, MJ Conboy, IM Conboy - Skeletal muscle, 2020 - Springer
Skeletal muscle is among the most age-sensitive tissues in mammal organisms. Significant
changes in its resident stem cells (ie, satellite cells, SCs), differentiated cells (ie, myofibers) …

Myeloid-derived growth factor alleviates non-alcoholic fatty liver disease alleviates in a manner involving IKKβ/NF-κB signaling

Y Ding, X Xu, B Meng, L Wang, B Zhu, B Guo… - Cell Death & …, 2023 - nature.com
Whether bone marrow modulates systemic metabolism remains unknown. Our recent study
suggested that myeloid-derived growth factor (MYDGF) improves insulin resistance. Here …

Myeloid-derived growth factor inhibits inflammation and alleviates endothelial injury and atherosclerosis in mice

B Meng, Y Li, Y Ding, X Xu, L Wang, B Guo, B Zhu… - Science …, 2021 - science.org
Whether bone marrow modulates systemic metabolism remains unknown. Here, we found
that (i) myeloid cell–specific myeloid-derived growth factor (MYDGF) deficiency exacerbated …

Nitric oxide generation and endothelial progenitor cells recruitment for improving hemocompatibility and accelerating endothelialization of tissue engineering heart …

Y Zhou, G Yan, S Wen, WY Yim, Z Wang… - Advanced Functional …, 2023 - Wiley Online Library
Tissue engineering heart valve (TEHV) offers great potential to overcome the limitations of
commercial artificial valves used in clinical practice as a permanent prosthetic valve …

MYDGF attenuates podocyte injury and proteinuria by activating Akt/BAD signal pathway in mice with diabetic kidney disease

M He, Y Li, L Wang, B Guo, W Mei, B Zhu, J Zhang… - Diabetologia, 2020 - Springer
Aims/hypothesis Myeloid-derived growth factor (MYDGF), mainly secreted by bone marrow-
derived cells, has been known to promote glucagon-like peptide-1 production and improve …

Structured wound angiogenesis instructs mesenchymal barrier compartments in the regenerating nerve

GP Bhat, A Maurizio, A Motta, P Podini, S Diprima… - Neuron, 2024 - cell.com
Organ injury stimulates the formation of new capillaries to restore blood supply raising
questions about the potential contribution of neoangiogenic vessel architecture to the …

Similar sequences but dissimilar biological functions of GDF11 and myostatin

J Suh, YS Lee - Experimental & molecular medicine, 2020 - nature.com
Abstract Growth differentiation factor 11 (GDF11) and myostatin (MSTN) are closely related
TGFβ family members that are often believed to serve similar functions due to their high …

Recent approaches for angiogenesis in search of successful tissue engineering and regeneration

LVK Reddy, D Murugan, M Mullick… - Current Stem Cell …, 2020 - ingentaconnect.com
Angiogenesis plays a central role in human physiology from reproduction and fetal
development to wound healing and tissue repair/regeneration. Clinically relevant therapies …

Hyaluronic Acid Facilitates Angiogenesis of Endothelial Colony Forming Cell Combining With Mesenchymal Stem Cell via CD44/ MicroRNA-139-5p Pathway

Y Luo, F Liang, X Wan, S Liu, L Fu, J Mo… - … in bioengineering and …, 2022 - frontiersin.org
Stem cells and progenitor cells have been identified as potential new therapeutic options for
severe limb ischemia to induce angiogenesis, and hyaluronic acid (HA) is commonly …