Microsporidia: a promising vector control tool for residual malaria transmission

T Bukhari, R Pevsner, JK Herren - Frontiers in Tropical Diseases, 2022 - frontiersin.org
Long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) have resulted in a
major decrease in malaria transmission. However, it has become apparent that malaria can …

Host-specific effects of a generalist parasite of mosquitoes

TG Zeferino, JC Koella - Scientific Reports, 2024 - nature.com
Microsporidians are obligate parasites of many animals, including mosquitoes. Some
microsporidians have been proposed as potential agents for the biological control of …

The promise and challenge of genetic biocontrol approaches for malaria elimination

S James, M Santos - Tropical Medicine and Infectious Disease, 2023 - mdpi.com
Malaria remains an ongoing public health challenge, with over 600,000 deaths in 2021, of
which approximately 96% occurred in Africa. Despite concerted efforts, the goal of global …

The gut commensal bacterium Enterococcus faecalis LX10 contributes to defending against Nosema bombycis infection in Bombyx mori

X Zhang, H Feng, J He, X Liang… - Pest Management …, 2022 - Wiley Online Library
BACKGROUND Microsporidia, a group of obligate intracellular fungal‐related parasites,
have been used as efficient biocontrol agents for agriculture and forestry pests due to their …

Microsporidia MB is found predominantly associated with Anopheles gambiae ss and Anopheles coluzzii in Ghana

J Akorli, EA Akorli, SNA Tetteh, GK Amlalo, M Opoku… - Scientific Reports, 2021 - nature.com
A vertically transmitted microsporidian, Microsporidia MB, with the ability to disrupt
Plasmodium development was reported in Anopheles arabiensis from Kenya, East Africa. To …

The Plasmodium transmission-blocking symbiont, Microsporidia MB, is vertically transmitted through Anopheles arabiensis germline stem cells

TO Onchuru, EE Makhulu, PC Ronnie… - PLoS …, 2024 - journals.plos.org
Microsporidia MB is a promising candidate for developing a symbiont-based strategy for
malaria control because it disrupts the capacity of An. arabiensis to transmit the Plasmodium …

Bioinformatics analysis of the Microsporidia sp. MB genome: a malaria transmission-blocking symbiont of the Anopheles arabiensis mosquito

LM Ang'ang'o, JK Herren, Ö Tastan Bishop - BMC genomics, 2024 - Springer
Background The use of microsporidia as a disease-transmission-blocking tool has garnered
significant attention. Microsporidia sp. MB, known for its ability to block malaria development …

[HTML][HTML] Insects and microbes: best friends from the nursery

E Chabanol, M Gendrin - Current Opinion in Insect Science, 2024 - Elsevier
Highlights•Insects associate with microbes early in life.•Insect microbiota:•helps digestion of
lignocellulose, proteins and fatty acids;•produces essential nutriments for its insect host (B …

Willingness to accept and participate in a Microsporidia MB-based mosquito release strategy: a community-based rapid assessment in western Kenya

T Bukhari, J Gichuhi, O Mbare, VA Ochwal, U Fillinger… - Malaria Journal, 2024 - Springer
Background Microsporidia MB, an endosymbiont naturally found in Anopheles mosquitoes
inhibits transmission of Plasmodium and is a promising candidate for a transmission …

Effect of Microsporidia MB infection on the development and fitness of Anopheles arabiensis under different diet regimes

GY Boanyah, LL Koekemoer, JK Herren, T Bukhari - Parasites & Vectors, 2024 - Springer
Abstract Background Microsporidia MB (MB) is a naturally occurring symbiont of Anopheles
and has recently been identified as having a potential to inhibit the transmission of …