Aminoacyl-tRNA synthesis

M Ibba, D Söll - Annual review of biochemistry, 2000 - annualreviews.org
▪ Abstract Aminoacyl-tRNAs are substrates for translation and are pivotal in determining how
the genetic code is interpreted as amino acids. The function of aminoacyl-tRNA synthesis is …

How selenium has altered our understanding of the genetic code

DL Hatfield, VN Gladyshev - Molecular and cellular biology, 2002 - Am Soc Microbiol
Selenium is an essential micronutrient in the diet of many life forms, including humans and
other mammals. Significant health benefits have been attributed to this element. It is rapidly …

Historical roles of selenium and selenoproteins in health and development: the good, the bad and the ugly

PA Tsuji, D Santesmasses, BJ Lee… - International journal of …, 2021 - mdpi.com
Selenium is a fascinating element that has a long history, most of which documents it as a
deleterious element to health. In more recent years, selenium has been found to be an …

The nuclear and cytoplasmic activities of RNA polymerase III, and an evolving transcriptome for surveillance

AC Kessler, RJ Maraia - Nucleic Acids Research, 2021 - academic.oup.com
A 1969 report that described biochemical and activity properties of the three eukaryotic RNA
polymerases revealed Pol III as highly distinguishable, even before its transcripts were …

Zebrafish in the sea of mineral (iron, zinc, and copper) metabolism

L Zhao, Z Xia, F Wang - Frontiers in pharmacology, 2014 - frontiersin.org
Iron, copper, zinc, and eight other minerals are classified as essential trace elements
because they present in minute in vivo quantities and are essential for life. Because either …

Selenium metabolism in zebrafish: multiplicity of selenoprotein genes and expression of a protein containing 17 selenocysteine residues

GV Kryukov, VN Gladyshev - Genes to Cells, 2000 - Wiley Online Library
Fish are an important source of selenium in human nutrition and the zebrafish is a potentially
useful model organism for the study of selenium metabolism and its role in biology and …

Computational identification of the selenocysteine tRNA (tRNASec) in genomes

D Santesmasses, M Mariotti… - PLoS computational …, 2017 - journals.plos.org
Selenocysteine (Sec) is known as the 21st amino acid, a cysteine analogue with selenium
replacing sulphur. Sec is inserted co-translationally in a small fraction of proteins called …

Evolution of selenocysteine‐containing proteins: Significance of identification and functional characterization of selenoproteins

VN Gladyshev, GV Kryukov - Biofactors, 2001 - Wiley Online Library
In the genetic code, UGA serves as either a signal for termination or a codon for
selenocysteine (Sec). Sec rarely occurs in protein and is different from other amino acids in …

[图书][B] Diversity of selenium functions in health and disease

R Brigelius-Flohé, H Sies - 2015 - books.google.com
This book brings together the accumulated evidence regarding selenium biochemistry and
trace element caused carcinogenesis. After the introduction to be written by Gerry Combs …

Selenocysteine tRNA[Ser]Sec: From Nonsense Suppressor tRNA to the Quintessential Constituent in Selenoprotein Biosynthesis

BA Carlson, BJ Lee, PA Tsuji, R Tobe, JM Park… - Selenium: its molecular …, 2016 - Springer
Abstract When selenocysteine (Sec) tRNA [Ser] Sec was originally discovered, it was
proposed to be the first nonsense suppressor tRNA found in mammalian and avian tissues …