GENA-LM: a family of open-source foundational DNA language models for long sequences

V Fishman, Y Kuratov, A Shmelev, M Petrov, D Penzar… - bioRxiv, 2023 - biorxiv.org
Recent advancements in genomics, propelled by artificial intelligence, have unlocked
unprecedented capabilities in interpreting genomic sequences, mitigating the need for …

Improving the performance of supervised deep learning for regulatory genomics using phylogenetic augmentation

AG Duncan, JA Mitchell, AM Moses - Bioinformatics, 2024 - academic.oup.com
Motivation Supervised deep learning is used to model the complex relationship between
genomic sequence and regulatory function. Understanding how these models make …

Genomics of a sexually selected sperm ornament and female preference in Drosophila

ZA Syed, RA Gomez, K Borziak, A Asif… - Nature Ecology & …, 2024 - nature.com
Our understanding of animal ornaments and the mating preferences driving their
exaggeration is limited by knowledge of their genetics. Post-copulatory sexual selection is …

Phylogenomic Insights into the Evolution and Origin of nematoda

X Qing, YM Zhang, S Sun, M Ahmed, WS Lo, W Bert… - bioRxiv, 2023 - biorxiv.org
The phylum Nematoda represents one of the most cosmopolitan and abundant metazoans
on Earth. In this study, we reconstructed the first phylogenomic tree for phylum Nematoda. A …

Experimental horizontal transfer of phage-derived genes to Drosophila confers innate immunity to parasitoids

RL Tarnopol, JA Tamsil, G Cinege, JH Ha, KI Verster… - Current Biology, 2024 - cell.com
Metazoan parasites have played a major role in shaping innate immunity in animals. Insect
hosts and parasitoid wasps are excellent models for illuminating how animal innate immune …

Whole genome phylogenomics helps to resolve the phylogenetic position of the Zygothrica genus group (Diptera, Drosophilidae) and the causes of previous …

MH Bessa, MS Gottschalk, LJ Robe - Molecular Phylogenetics and …, 2024 - Elsevier
Abstract Incomplete Lineage Sorting (ILS) and introgression are among the two main factors
causing incongruence between gene and species trees. Advances in phylogenomic studies …

Genital coupling and copulatory wounding in the Drosophila rufa species complex: comparison with the D. auraria species complex (Diptera: Drosophilidae)

H Omiya, M Onuma, T Awasaki… - Biological Journal of …, 2024 - academic.oup.com
In sexually reproducing animals, genital morphology is usually divergent among closely
related species, which can lead to a mismatch of genital coupling (ie mechanical isolation) …

PLOS Biology and the life sciences in 2024

D Routledge, PLOS Biology Staff Editors - PLoS biology, 2024 - journals.plos.org
PLOS Biology and the life sciences in 2024 | PLOS Biology Skip to main content
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Molecular phylogeny and species diversity of the genus Dichaetophora Duda and related taxa (Diptera: Drosophilidae)

TK Katoh, JM Chen, JH Yang, G Zhang, L Wang… - Molecular Phylogenetics …, 2024 - Elsevier
Our intensive surveys of wild drosophilids in East and Southeast Asia discovered a great
species diversity (more than 100 putatively new species) of the genus Dichaetophora, which …

FlaHMM: unistrand flamenco-like piRNA cluster prediction in Drosophila species using hidden Markov models

MA Trapotsi, J van Lopik, GJ Hannon… - NAR Genomics and …, 2024 - academic.oup.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that are essential for
transposon control in animal gonads. In Drosophila ovarian somatic cells, piRNAs are …