Virulence factors in carbapenem-resistant hypervirulent Klebsiella pneumoniae

G Mendes, ML Santos, JF Ramalho, A Duarte… - Frontiers in …, 2023 - frontiersin.org
Hypervirulence and carbapenem-resistant have emerged as two distinct evolutionary
pathotypes of Klebsiella pneumoniae, with both reaching their epidemic success and posing …

Carbapenem-resistant Klebsiella pneumoniae: the role of plasmids in emergence, dissemination, and evolution of a major clinical challenge

V Di Pilato, S Pollini, V Miriagou… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction Klebsiella pneumoniae is a major agent of healthcare-associated infections and
a cause of some community-acquired infections, including severe bacteremic infections …

Antibiotic susceptibility surveillance in the Punjab Province of Pakistan: findings and implications

Z Saleem, A Haseeb, SSA Abuhussain, CE Moore… - Medicina, 2023 - mdpi.com
Background and Objectives: The increase in antimicrobial resistance (AMR) across
countries has seriously impacted the effective management of infectious diseases, with …

Uropathogens, urinary tract infections, the host-pathogen interactions and treatment

P Behzadi, HA García-Perdomo… - Frontiers in …, 2023 - frontiersin.org
Both Gram-negative and Gram-positive bacteria as well as fungi are responsible for urinary
tract infections (UTIs). However, among Gram-negative bacterial agents, uropathogenic E …

Pan-Genome Plasticity and Virulence Factors: A Natural Treasure Trove for Acinetobacter baumannii

T Karampatakis, K Tsergouli, P Behzadi - Antibiotics, 2024 - mdpi.com
Acinetobacter baumannii is a Gram-negative pathogen responsible for a variety of
community-and hospital-acquired infections. It is recognized as a life-threatening pathogen …

The Biological and Regulatory Role of Type VI Secretion System of Klebsiella pneumoniae

W Liu, M Li, S Cao, HM Ishaq, H Zhao… - Infection and Drug …, 2023 - Taylor & Francis
Bacteria communicate with their surroundings through diverse secretory systems, and the
recently discovered Type VI Secretion System (T6SS) has gained significant attention …

Heteroresistance to Colistin in Clinical Isolates of Klebsiella pneumoniae Producing OXA-48

I Sánchez-León, T García-Martínez, SM Diene… - Antibiotics, 2023 - mdpi.com
Heteroresistance to colistin can be defined as the presence of resistant subpopulations in an
isolate that is susceptible to this antibiotic. Colistin resistance in Gram-negative bacteria is …

The innate and adaptive immune system in human urinary system

P Behzadi, CH Kim, EA Pawlak… - Frontiers in …, 2023 - frontiersin.org
The urinary, immune, and nervous systems communicate with each other to create an
effective network in a healthy human body. The kidneys and the bladder are known as the …

Risk Factors and Mortality of Elderly Patients with Hospital-Acquired Pneumonia of Carbapenem-Resistant Klebsiella pneumoniae Infection

C Zhou, L Sun, H Li, L Huang, X Liu - Infection and Drug …, 2023 - Taylor & Francis
Purpose Hospital-acquired pneumonia (HAP) caused by carbapenem-resistant K.
pneumoniae (CRKP), especially in elderly patients, results in high morbidity and mortality …

Clinical Characteristics and Prognosis of Hospital-Acquired Klebsiella pneumoniae Bacteremic Pneumonia versus Escherichia coli Bacteremic Pneumonia: A …

F Li, J Zhu, Y Hang, Y Chen, S Gu, S Peng… - Infection and Drug …, 2023 - Taylor & Francis
Objective This research aimed to investigate the variations in clinical features and prognosis
of HABP caused by E. coli and K. pneumoniae. We also aimed to evaluate the risk variables …