Epithelial-to-mesenchymal transition (EMT) is associated with metastasis formation as well
as with generation and maintenance of cancer stem cells. In this way, EMT contributes to …

Alternative precursor-mRNA splicing is a key mechanism for regulating gene expression in
mammals and is controlled by specialized RNA-binding proteins. The misregulation of …

Direct reprogramming of glia into neurons is a potentially promising approach for the
replacement of neurons lost to injury or neurodegenerative disorders. Knockdown of the …

Crustacean aquaculture is expected to be a major source of fishery commodities in the near
future. Hemocytes are key players of the immune system in shrimps; however, their …

RNA binding proteins (RBPs) are a large and diverse class of proteins that regulate all
aspects of RNA biology. As RBP dysregulation has been implicated in a number of human …

Although in vivo reprogramming of astrocytes into neurons holds promise for treating
neurodegenerative disorders, protocols to achieve it are complex and inefficient. A recent …

A holy grail of regenerative medicine is to replenish the cells that are lost due to disease.
The adult mammalian central nervous system (CNS) has, however, largely lost such a …

Polypyrimidine tract‐binding protein (PTB), as a member of the heterogeneous nuclear
ribonucleoprotein family, functions by rapidly shuttling between the nucleus and the …

Alternative splicing patterns are regulated by RNA binding proteins that assemble onto each
pre-mRNA to form a complex RNP structure. The polypyrimidine tract binding protein, PTB …

Circular RNAs (circRNAs) are highly expressed in the brain and their expression increases
during neuronal differentiation. The factors regulating circRNAs in the developing mouse …