Tumor suppressors BTG1 and BTG2: Beyond growth control
L Yuniati, B Scheijen, LT van der Meer… - Journal of cellular …, 2019 - Wiley Online Library
Since the identification of B‐cell translocation gene 1 (BTG1) and BTG2 as antiproliferation
genes more than two decades ago, their protein products have been implicated in a variety …
genes more than two decades ago, their protein products have been implicated in a variety …
BTG2: a rising star of tumor suppressors
B Mao, Z Zhang, G Wang - International journal of …, 2014 - spandidos-publications.com
B-cell translocation gene 2 (BTG2), the first gene identified in the BTG/TOB gene family, is
involved in many biological activities in cancer cells acting as a tumor suppressor. The BTG2 …
involved in many biological activities in cancer cells acting as a tumor suppressor. The BTG2 …
Single-cell analysis of the muscle stem cell hierarchy identifies heterotypic communication signals involved in skeletal muscle regeneration
AJ De Micheli, EJ Laurilliard, CL Heinke… - Cell reports, 2020 - cell.com
Muscle regeneration relies on the regulation of muscle stem cells (MuSCs) through
paracrine signaling interactions. We analyzed muscle regeneration in mice using single-cell …
paracrine signaling interactions. We analyzed muscle regeneration in mice using single-cell …
Child abuse, depression, and methylation in genes involved with stress, neural plasticity, and brain circuitry
Objectives To determine whether epigenetic markers predict dimensional ratings of
depression in maltreated children. Method A genome-wide methylation study was …
depression in maltreated children. Method A genome-wide methylation study was …
Urinary Exosomal miRNAs as biomarkers of bladder Cancer and experimental verification of mechanism of miR-93-5p in bladder Cancer
H Lin, X Shi, H Li, J Hui, R Liu, Z Chen, Y Lu, W Tan - Bmc Cancer, 2021 - Springer
Background Bladder cancer (BC) is one of the most common malignancies globally. Early
diagnosis of it can significantly improve patients' survival and quality of life. Urinary …
diagnosis of it can significantly improve patients' survival and quality of life. Urinary …
Overexpression of Tbx20 in adult cardiomyocytes promotes proliferation and improves cardiac function after myocardial infarction
Background—Adult mammalian cardiomyocytes (CMs) have the potential to proliferate, but
this is not sufficient to generate adequate CMs after myocardial infarction (MI). The …
this is not sufficient to generate adequate CMs after myocardial infarction (MI). The …
[HTML][HTML] Single-cell transcriptome profiling of mouse and hESC-derived pancreatic progenitors
Human embryonic stem cells (hESCs) are a potential unlimited source of insulin-producing
β cells for diabetes treatment. A greater understanding of how β cells form during embryonic …
β cells for diabetes treatment. A greater understanding of how β cells form during embryonic …
Schwann cell autophagy counteracts the onset and chronification of neuropathic pain
S Marinelli, F Nazio, A Tinari, L Ciarlo, M D'Amelio… - PAIN®, 2014 - Elsevier
Axonal degeneration in peripheral nerves after injury is accompanied by myelin degradation
initiated by Schwann cells (SCs). These cells activate autophagy, a ubiquitous cytoprotective …
initiated by Schwann cells (SCs). These cells activate autophagy, a ubiquitous cytoprotective …
miR-302 is required for timing of neural differentiation, neural tube closure, and embryonic viability
The evolutionarily conserved miR-302 family of microRNAs is expressed during early
mammalian embryonic development. Here, we report that deletion of miR-302a-d in mice …
mammalian embryonic development. Here, we report that deletion of miR-302a-d in mice …
Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer's disease
In adult mammals, neural progenitors located in the dentate gyrus retain their ability to
generate neurons and glia throughout lifetime. In rodents, increased production of new …
generate neurons and glia throughout lifetime. In rodents, increased production of new …