Tumor suppressors BTG1 and BTG2: Beyond growth control

L Yuniati, B Scheijen, LT van der Meer… - Journal of cellular …, 2019 - Wiley Online Library
Since the identification of B‐cell translocation gene 1 (BTG1) and BTG2 as antiproliferation
genes more than two decades ago, their protein products have been implicated in a variety …

BTG2: a rising star of tumor suppressors

B Mao, Z Zhang, G Wang - International journal of …, 2014 - spandidos-publications.com
B-cell translocation gene 2 (BTG2), the first gene identified in the BTG/TOB gene family, is
involved in many biological activities in cancer cells acting as a tumor suppressor. The BTG2 …

Single-cell analysis of the muscle stem cell hierarchy identifies heterotypic communication signals involved in skeletal muscle regeneration

AJ De Micheli, EJ Laurilliard, CL Heinke… - Cell reports, 2020 - cell.com
Muscle regeneration relies on the regulation of muscle stem cells (MuSCs) through
paracrine signaling interactions. We analyzed muscle regeneration in mice using single-cell …

Child abuse, depression, and methylation in genes involved with stress, neural plasticity, and brain circuitry

N Weder, H Zhang, K Jensen, BZ Yang, A Simen… - Journal of the American …, 2014 - Elsevier
Objectives To determine whether epigenetic markers predict dimensional ratings of
depression in maltreated children. Method A genome-wide methylation study was …

Urinary Exosomal miRNAs as biomarkers of bladder Cancer and experimental verification of mechanism of miR-93-5p in bladder Cancer

H Lin, X Shi, H Li, J Hui, R Liu, Z Chen, Y Lu, W Tan - Bmc Cancer, 2021 - Springer
Background Bladder cancer (BC) is one of the most common malignancies globally. Early
diagnosis of it can significantly improve patients' survival and quality of life. Urinary …

Overexpression of Tbx20 in adult cardiomyocytes promotes proliferation and improves cardiac function after myocardial infarction

F Xiang, M Guo, KE Yutzey - Circulation, 2016 - Am Heart Assoc
Background—Adult mammalian cardiomyocytes (CMs) have the potential to proliferate, but
this is not sufficient to generate adequate CMs after myocardial infarction (MI). The …

[HTML][HTML] Single-cell transcriptome profiling of mouse and hESC-derived pancreatic progenitors

NAJ Krentz, MYY Lee, EE Xu, SLJ Sproul, A Maslova… - Stem cell reports, 2018 - cell.com
Human embryonic stem cells (hESCs) are a potential unlimited source of insulin-producing
β cells for diabetes treatment. A greater understanding of how β cells form during embryonic …

Schwann cell autophagy counteracts the onset and chronification of neuropathic pain

S Marinelli, F Nazio, A Tinari, L Ciarlo, M D'Amelio… - PAIN®, 2014 - Elsevier
Axonal degeneration in peripheral nerves after injury is accompanied by myelin degradation
initiated by Schwann cells (SCs). These cells activate autophagy, a ubiquitous cytoprotective …

miR-302 is required for timing of neural differentiation, neural tube closure, and embryonic viability

RJ Parchem, N Moore, JL Fish, JG Parchem, TT Braga… - Cell reports, 2015 - cell.com
The evolutionarily conserved miR-302 family of microRNAs is expressed during early
mammalian embryonic development. Here, we report that deletion of miR-302a-d in mice …

Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer's disease

K Richetin, C Leclerc, N Toni, T Gallopin, S Pech… - Brain, 2015 - academic.oup.com
In adult mammals, neural progenitors located in the dentate gyrus retain their ability to
generate neurons and glia throughout lifetime. In rodents, increased production of new …