Aging, obesity, sarcopenia and the effect of diet and exercise intervention

G Colleluori, DT Villareal - Experimental gerontology, 2021 - Elsevier
The number of adults 65 years and older is increasing worldwide and will represent the 20%
of the population by 2030. Half of them will suffer from obesity. The decline in muscle mass …

[HTML][HTML] Sarcopenia and muscle aging: a brief overview

T Dao, AE Green, YA Kim, SJ Bae… - Endocrinology and …, 2020 - synapse.koreamed.org
The world is facing the new challenges of an aging population, and understanding the
process of aging has therefore become one of the most important global concerns …

[HTML][HTML] International exercise recommendations in older adults (ICFSR): expert consensus guidelines

M Izquierdo, RA Merchant, JE Morley, SD Anker… - The journal of nutrition …, 2021 - Springer
The human ageing process is universal, ubiquitous and inevitable. Every physiological
function is being continuously diminished. There is a range between two distinct phenotypes …

Calorie restriction and aging in humans

EW Flanagan, J Most, JT Mey… - Annual review of …, 2020 - annualreviews.org
Calorie restriction (CR), the reduction of dietary intake below energy requirements while
maintaining optimal nutrition, is the only known nutritional intervention with the potential to …

Hesperidin: A therapeutic agent for obesity

H Xiong, J Wang, Q Ran, G Lou, C Peng… - Drug design …, 2019 - Taylor & Francis
Obesity is a chronic metabolic disease caused by multiple factors and is considered to be a
risk factor for type 2 diabetes, cardiovascular disease, hypertension, stroke and various …

Mesenchymal stromal cells ameliorate diabetes‐induced muscle atrophy through exosomes by enhancing AMPK/ULK1‐mediated autophagy

J Song, J Liu, C Cui, H Hu, N Zang… - Journal of cachexia …, 2023 - Wiley Online Library
Background Diabetes and obesity are associated with muscle atrophy that reduces life
quality and lacks effective treatment. Mesenchymal stromal cell (MSC)‐based therapy can …

Effect of exercise training on body composition and inflammatory cytokine levels in overweight and obese individuals: a systematic review and network meta-analysis

S Wang, H Zhou, C Zhao, H He - Frontiers in immunology, 2022 - frontiersin.org
Objective This study aimed to compare and rank the effectiveness of aerobic exercise (AE),
resistance training (RT), combined aerobic and resistance training (CT), and high-intensity …

Aerobic exercise and resistance exercise alleviate skeletal muscle atrophy through IGF-1/IGF-1R-PI3K/Akt pathway in mice with myocardial infarction

L Feng, B Li, Y Xi, M Cai, Z Tian - American Journal of …, 2022 - journals.physiology.org
Myocardial infarction (MI)-induced heart failure (HF) is commonly accompanied with
profound effects on skeletal muscle. With the process of MI-induced HF, perturbations in …

C‐terminal agrin fragment as a biomarker of muscle wasting and weakness: a narrative review

E Monti, F Sarto, R Sartori, G Zanchettin… - Journal of Cachexia …, 2023 - Wiley Online Library
Ageing is accompanied by an inexorable loss of muscle mass and functionality and
represents a major risk factor for numerous diseases such as cancer, diabetes and …

The mechanisms and treatments for sarcopenia: could exosomes be a perspective research strategy in the future?

S Rong, L Wang, Z Peng, Y Liao, D Li… - Journal of cachexia …, 2020 - Wiley Online Library
The age‐related loss of muscle mass and muscle function known as sarcopenia is a primary
contributor to the problems faced by the old people. Sarcopenia has been a major public …