Background Over the past 25 years, researchers have performed> 120 randomized
controlled trials (RCTs) illustrating short courses to be non-inferior to long courses of …

The incidence of infections caused by bacteria that are resistant to antibiotics is constantly
increasing. In Europe alone, it has been estimated that each year about 33′ 000 deaths are …

Background A growing number of studies have demonstrated similar outcomes with shorter
courses of antibiotics for bacterial infections. Immunocompromised patients are frequently …

Like all fields of medicine, Infectious Diseases is rife with dogma that underpins much
clinical practice. In this study, we discuss 2 specific examples of historical practice that have …

Background Limited data are available to guide effective antibiotic durations for hospitalized
patients with complicated urinary tract infections (cUTIs). Methods We conducted an …

Background We aim to compare the effect of short versus long treatment duration in Gram-
negative bacteremia on all-cause mortality in pre-specified sub-groups. Methods Individual …

Purpose of review To review recently published evidence relevant to Staphylococcus aureus
bacteremia (SAB). Recent findings Staphylococcus aureus is the most common pathogen …

Introduction There is no consensus regarding optimal duration of antibiotic therapy for
Pseudomonas aeruginosa bacteremia. We aimed to evaluate the impact of short antibiotic …

Background Despite the availability of antimicrobial therapies, gram-negative bacteremia
remains a significant cause of morbidity and mortality on a global level. Recent randomized …

The square root of this value is used as an estimate of the standard error to make a normal
approximation to the width of the confidence interval. This holds whether or not ties are …