Anti-epileptic drugs (AEDs) are an important group of drugs of several generations, ranging
from the oldest phenobarbital (1912) to the most recent cenobamate (2019). Cannabidiol …

Next-generation sequencing (NGS) has contributed to the identification of many monogenic
epilepsy syndromes and is favouring earlier and more accurate diagnosis in a subset of …

Abstract Objective Study 311 (NCT02849626) was a global, multicenter, open‐label, single‐
arm study that assessed safety, tolerability, pharmacokinetics, and pharmacokinetics …

Purpose Positron emission tomography (PET) with 18F-fluorodeoxyglucose ([18F]-FDG) has
been increasingly applied in precise localization of epileptogenic focus in epilepsy patients …

Epilepsy is one of the most frequent neurological conditions with an estimated prevalence of
more than 50 million people worldwide and an annual incidence of two million. Although …

Objective Heterozygous variants in KCNQ2 or, more rarely, KCNQ3 genes are responsible
for early‐onset developmental/epileptic disorders characterized by heterogeneous clinical …

Background and objective: Epileptic seizures are associated with a higher incidence of
Developmental Disabilities and Cerebral Palsy. Early evaluation and management of …

The review presents data from the last few years on bioanalytical methods used in
therapeutic drug monitoring (TDM) of the 1st–3rd generation and the newest antiepileptic …

Background Contemporary research indicates the role of neuroinflammation/inflammatory
markers in epilepsy. In addition, comorbidities such as anxiety and poor health-related …

Epilepsy affects approximately 10 million children globally. Antiepileptic drugs (AEDs) are
among the most frequent causes of drug hypersensitivity reactions (DHRs), especially …