The search for neuroprotective strategies in stroke
GH Danton, WD Dietrich - American journal of …, 2004 - Am Soc Neuroradiology
In fiscal year 2001, the National Institutes of Health (NIH) total research expenditures for
stroke reached nearly $239 million. A significant focus of stroke research is the development …
stroke reached nearly $239 million. A significant focus of stroke research is the development …
[HTML][HTML] Assessment of serum UCH-L1 and GFAP in acute stroke patients
A rapid and reliable diagnostic test to distinguish ischemic from hemorrhagic stroke in
patients presenting with stroke-like symptoms is essential to optimize management and …
patients presenting with stroke-like symptoms is essential to optimize management and …
Cerebrovascular thromboprophylaxis in mice by erythrocyte-coupled tissue-type plasminogen activator
Background—Cerebrovascular thrombosis is a major source of morbidity and mortality after
surgery, but thromboprophylaxis in this setting is limited because of the formidable risk of …
surgery, but thromboprophylaxis in this setting is limited because of the formidable risk of …
Early and late recurrence of ischemic lesion on MRI: evidence for a prolonged stroke-prone state?
Background: Based on previous observations of a high rate of ischemic lesion recurrence on
diffusion-weighted imaging (DWI) within 1 week after an acute ischemic stroke, the authors …
diffusion-weighted imaging (DWI) within 1 week after an acute ischemic stroke, the authors …
Risk factors for early and late recurrent ischemic strokes
HM Elnady, GF Mohammed, HK Elhewag… - The Egyptian journal of …, 2020 - Springer
Background Nationally, information regarding risk factors for early and late recurrence of
ischemic stroke is limited. Objectives The aim of this study was to identify the risk factors for …
ischemic stroke is limited. Objectives The aim of this study was to identify the risk factors for …
Characterization of a thromboembolic photochemical model of repeated stroke in mice
Many stroke research groups utilize the model of middle cerebral artery occlusion induced
by insertion of an intraluminal thread, owing to its pragmatism and reliability of cerebral …
by insertion of an intraluminal thread, owing to its pragmatism and reliability of cerebral …
Transient ischemia elicits a sustained enhancement of thrombus development in the cerebral microvasculature: effects of anti-thrombotic therapy
YH Tang, S Vital, J Russell, H Seifert… - Experimental …, 2014 - Elsevier
Objective While transient ischemic attack (TIA) is a well-known harbinger of ischemic stroke,
the mechanisms that link TIA to subsequent strokes remain poorly understood. The overall …
the mechanisms that link TIA to subsequent strokes remain poorly understood. The overall …
Development of a model of recurrent stroke consisting of a mild transient stroke followed by a second moderate stroke in rats
M Qiao, Z Zhao, PA Barber, T Foniok, S Sun… - Journal of neuroscience …, 2009 - Elsevier
Recurrent stroke often consists of a transient ischemic attack or mild stroke followed by a
moderate stroke. Lacking is knowledge of the mechanisms of interaction of such multiple …
moderate stroke. Lacking is knowledge of the mechanisms of interaction of such multiple …
Adaptation and sensitization to proteotoxic stress
RK Leak - Dose-Response, 2014 - journals.sagepub.com
Although severe stress can elicit toxicity, mild stress often elicits adaptations. Here we
review the literature on stress-induced adaptations versus stress sensitization in models of …
review the literature on stress-induced adaptations versus stress sensitization in models of …
The beneficial effect of mild hypothermia in a rat model of repeated thromboembolic insults
The post-thrombotic brain has recently been reported to have an enhanced vulnerability to a
second embolic insult. Although postischemic hypothermia is neuroprotective in global and …
second embolic insult. Although postischemic hypothermia is neuroprotective in global and …