[HTML][HTML] The quest for multiscale brain modeling
E D'Angelo, V Jirsa - Trends in neurosciences, 2022 - cell.com
Addressing the multiscale organization of the brain, which is fundamental to the dynamic
repertoire of the organ, remains challenging. In principle, it should be possible to model …
repertoire of the organ, remains challenging. In principle, it should be possible to model …
Questions and controversies in the study of time-varying functional connectivity in resting fMRI
The brain is a complex, multiscale dynamical system composed of many interacting regions.
Knowledge of the spatiotemporal organization of these interactions is critical for establishing …
Knowledge of the spatiotemporal organization of these interactions is critical for establishing …
[HTML][HTML] Geometric constraints on human brain function
The anatomy of the brain necessarily constrains its function, but precisely how remains
unclear. The classical and dominant paradigm in neuroscience is that neuronal dynamics …
unclear. The classical and dominant paradigm in neuroscience is that neuronal dynamics …
Methodological considerations for studying neural oscillations
T Donoghue, N Schaworonkow… - European journal of …, 2022 - Wiley Online Library
Neural oscillations are ubiquitous across recording methodologies and species, broadly
associated with cognitive tasks, and amenable to computational modelling that investigates …
associated with cognitive tasks, and amenable to computational modelling that investigates …
A cross-disorder connectome landscape of brain dysconnectivity
MP van den Heuvel, O Sporns - Nature reviews neuroscience, 2019 - nature.com
Many human brain disorders are associated with characteristic alterations in the structural
and functional connectivity of the brain. In this article, we explore how commonalities and …
and functional connectivity of the brain. In this article, we explore how commonalities and …
Heritability and interindividual variability of regional structure-function coupling
White matter structural connections are likely to support flow of functional activation or
functional connectivity. While the relationship between structural and functional connectivity …
functional connectivity. While the relationship between structural and functional connectivity …
[HTML][HTML] Neuronal excitation/inhibition imbalance: core element of a translational perspective on Alzheimer pathophysiology
Our incomplete understanding of the link between Alzheimer's Disease pathology and
symptomatology is a crucial obstacle for therapeutic success. Recently, translational studies …
symptomatology is a crucial obstacle for therapeutic success. Recently, translational studies …
The dynamics of resting fluctuations in the brain: metastability and its dynamical cortical core
In the human brain, spontaneous activity during resting state consists of rapid transitions
between functional network states over time but the underlying mechanisms are not …
between functional network states over time but the underlying mechanisms are not …
[HTML][HTML] The virtual epileptic patient: individualized whole-brain models of epilepsy spread
Individual variability has clear effects upon the outcome of therapies and treatment
approaches. The customization of healthcare options to the individual patient should …
approaches. The customization of healthcare options to the individual patient should …
Activity flow over resting-state networks shapes cognitive task activations
Resting-state functional connectivity (FC) has helped reveal the intrinsic network
organization of the human brain, yet its relevance to cognitive task activations has been …
organization of the human brain, yet its relevance to cognitive task activations has been …