Dynamin, the founding member of a family of dynamin-like proteins (DLPs) implicated in
membrane remodelling, has a critical role in endocytic membrane fission events. The use of …

Dynamins are large GTPases that belong to a protein superfamily that, in eukaryotic cells,
includes classical dynamins, dynamin-like proteins, OPA1, Mx proteins, mitofusins and …

We have recently characterized three yeast gene products (Vps35p, Vps29p, and Vps30p)
as candidate components of the sorting machinery required for the endosome-to-Golgi …

Mitochondria exist as a dynamic tubular network with projections that move, break, and
reseal in response to local environmental changes. We present evidence that a human …

The collection of vacuolar protein sorting mutants (vps mutants) in Saccharomyces
cerevisiae comprises of 41 complementation groups. The vacuoles in these mutant strains …

Little is known about the mechanism of mitochondrial division. We show here that
mitochondria are disrupted by mutations in a C. elegans dynamin-related protein (DRP-1) …

TEMPERATURE-sensitive paralysis is the most striking defect of adult Drosophila carrying
the shibire mutation1. This is believed to be due to a reversible block of endocytosis, which …

▪ Abstract Dynamin, a 100-kDa GTPase, is an essential component of vesicle formation in
receptor-mediated endocytosis, synaptic vesicle recycling, caveolae internalization, and …

The role of human dynamin in receptor-mediated endocytosis was investigated by transient
expression of GTP-binding domain mutants in mammalian cells. Using assays which detect …

Mx proteins are interferon‐induced GTPases that belong to the dynamin superfamily of large
GTPases. Similarities include a high molecular weight, a propensity to self‐assemble, a …