Recent advances in small organic molecules as DNA intercalating agents: Synthesis, activity, and modeling
A Rescifina, C Zagni, MG Varrica, V Pistarà… - European journal of …, 2014 - Elsevier
The interaction of small molecules with DNA plays an essential role in many biological
processes. As DNA is often the target for majority of anticancer and antibiotic drugs, study …
processes. As DNA is often the target for majority of anticancer and antibiotic drugs, study …
Overview of coumarin-fused-coumarins: synthesis, photophysical properties and their applications
M Sarmah, K Chutia, D Dutta, P Gogoi - Organic & Biomolecular …, 2022 - pubs.rsc.org
Coumarin-fused-coumarins have attracted significant attention in the scientific world owing
to their boundless applications in interdisciplinary areas. Various synthetic pathways have …
to their boundless applications in interdisciplinary areas. Various synthetic pathways have …
DNA Intercalating RuII Polypyridyl Complexes as Effective Photosensitizers in Photodynamic Therapy
C Mari, V Pierroz, R Rubbiani, M Patra… - … A European Journal, 2014 - Wiley Online Library
Six substitutionally inert [RuII (bipy) 2dppz] 2+ derivatives (bipy= 2, 2′‐bipyridine, dppz=
dipyrido [3, 2‐a: 2′, 3′‐c] phenazine) bearing different functional groups on the dppz …
dipyrido [3, 2‐a: 2′, 3′‐c] phenazine) bearing different functional groups on the dppz …
Photo-induced uncaging of a specific Re (I) organometallic complex in living cells
A Leonidova, V Pierroz, R Rubbiani, Y Lan… - Chemical …, 2014 - pubs.rsc.org
In the last decades, a large number of organometallic complexes have shown promising anti-
proliferative activity towards different cancer cell lines. However, these compounds generally …
proliferative activity towards different cancer cell lines. However, these compounds generally …
Naphthopyranones–isolation, bioactivity, biosynthesis and synthesis
CD Donner - Natural Product Reports, 2015 - pubs.rsc.org
Covering: up to 2014 The 1H-naphtho [2, 3-c] pyran-1-one (naphthopyranone) moiety forms
the structural framework of a group of secondary metabolites that have been isolated from a …
the structural framework of a group of secondary metabolites that have been isolated from a …
Synthetic remodeling of the chartreusin pathway to tune antiproliferative and antibacterial activities
N Ueberschaar, Z Xu, K Scherlach… - Journal of the …, 2013 - ACS Publications
Natural products of the benzonaphthopyranone class, such as chartreusin, elsamicin A,
gilvocarcin, and polycarcin, represent potent leads for urgently needed anticancer …
gilvocarcin, and polycarcin, represent potent leads for urgently needed anticancer …
Increased lipophilicity of halogenated ruthenium (II) polypyridyl complexes leads to decreased phototoxicity in vitro when used as photosensitizers for photodynamic …
S Roy, E Colombo, R Vinck, C Mari, R Rubbiani… - …, 2020 - Wiley Online Library
In the fight against cancer, photodynamic therapy is generating great interest thanks to its
ability to selectively kill cancer cells without harming healthy tissues. In this field, ruthenium …
ability to selectively kill cancer cells without harming healthy tissues. In this field, ruthenium …
Selective photorelease of an organometallic-containing enzyme inhibitor
A Leonidova, C Mari, C Aebersold, G Gasser - Organometallics, 2016 - ACS Publications
Histone deacetylases (HDACs) are regarded as promising targets in cancer and a growing
number of other diseases due to their crucial involvement in epigenetics and cellular …
number of other diseases due to their crucial involvement in epigenetics and cellular …
Induction of cytotoxicity through photorelease of aminoferrocene
A Leonidova, P Anstaett, V Pierroz, C Mari… - Inorganic …, 2015 - ACS Publications
Reactive oxygen species (ROS)-activated aminoferrocene-based anticancer prodrug
candidates successfully take advantage of intrinsically high amounts of ROS in tumor …
candidates successfully take advantage of intrinsically high amounts of ROS in tumor …
Ultrafast and Multichannel Generation of the Triplet State in DNA-Intercalated Gilvocarcin V for an Enhanced Photoaddition Reaction
P Jin, X Wang, M Jia, X He, H Pan… - The Journal of Physical …, 2024 - ACS Publications
Gilvocarcin V (GV) is a natural antibiotic exhibiting excellent antitumor activities and
remarkably low toxicity in near-ultraviolet or visible light-dependent treatment …
remarkably low toxicity in near-ultraviolet or visible light-dependent treatment …