Acute respiratory distress syndrome (ARDS) is a syndrome of acute respiratory failure
caused by noncardiogenic pulmonary edema. Despite five decades of basic and clinical …

Acute kidney injury (AKI) has emerged as a major public health problem that affects millions
of patients worldwide and leads to decreased survival and increased progression of …

The epithelial sodium channel (ENaC) is composed of three homologous subunits and
allows the flow of Na+ ions across high resistance epithelia, maintaining body salt and water …

Hypertension, or elevated arterial blood pressure, is a been operationally defined as the
blood pressure level substantial public health problem, affecting 25% of the above which …

BACKGROUND The use of antenatal steroid therapy is common in pregnancy. In early
pregnancy, steroids may be used in women for the treatment of recurrent miscarriage or fetal …

The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra,
forms a high-resistance but adaptable barrier that surveils its mechanochemical …

The recently discovered epithelial sodium channel (ENaC)/degenerin (DEG) gene family
encodes sodium channels involved in various cell functions in metazoans. Subfamilies …

The apical (outward-facing) membranes of high-resistance epithelia contain Na+ channels,
traditionally identified by their sensitivity to block by the K (+)-sparing diuretic amiloride …

Developmental lung biology is a field that has the potential for significant human impact:
lung disease at the extremes of age continues to cause major morbidity and mortality …

A dietary potassium load induces a rapid kaliuresis and natriuresis, which may occur even
before plasma potassium and aldosterone (aldo) levels increase. Here we sought to gain …