Synthetic methodologies of achiral diarylmethanols, diaryl and triarylmethanes (TRAMs) and medicinal properties of diaryl and triarylmethanes-an overview
The last decade has witnessed a high demand of various synthetic approaches towards
bioactive achiral diarylmethanols, diaryl and triarylmethanes and the molecules derived …
bioactive achiral diarylmethanols, diaryl and triarylmethanes and the molecules derived …
Chiral 1, 1-diaryl compounds as important pharmacophores
D Ameen, TJ Snape - MedChemComm, 2013 - pubs.rsc.org
Compounds containing a 1, 1-diaryl motif are numerous, and compounds of this type have
found use as catalysts and molecular building blocks, however, this review focusses solely …
found use as catalysts and molecular building blocks, however, this review focusses solely …
Antimalarial activity of small-molecule benzothiazole hydrazones
We synthesized a new series of conjugated hydrazones that were found to be active against
malaria parasite in vitro, as well as in vivo in a murine model. These hydrazones …
malaria parasite in vitro, as well as in vivo in a murine model. These hydrazones …
[HTML][HTML] Oxidative stress generated during monensin treatment contributes to altered Toxoplasma gondii mitochondrial function
RA Charvat, G Arrizabalaga - Scientific reports, 2016 - nature.com
The ionophore monensin displays potent activities against several coccidian parasites of
veterinary and medical importance including the opportunistic pathogen of humans …
veterinary and medical importance including the opportunistic pathogen of humans …
Metal-Free, Acid/Phosphine-Induced Regioselective Thiolation of p-Quinone Methides with Sodium Aryl/Alkyl Sulfinates
B Xiong, S Xu, Y Liu, KW Tang… - The Journal of Organic …, 2021 - ACS Publications
A simple and efficient method for the regioselective thiolation of p-quinone methides with
sodium aryl/alkyl sulfinates has been established using an acid/phosphine-induced radical …
sodium aryl/alkyl sulfinates has been established using an acid/phosphine-induced radical …
Reactivity vs. selectivity of quinone methides: synthesis of pharmaceutically important molecules, toxicity and biological applications
Quinone methides (QMs) are considered to be highly reactive intermediates because of their
aromatization both in chemical and biological systems. Being highly accessible, quinone …
aromatization both in chemical and biological systems. Being highly accessible, quinone …
Overview on the recent strategies for the enantioselective synthesis of 1, 1‐diarylalkanes, triarylmethanes and related molecules containing the diarylmethine …
There has recently been an increased interest in active pharmaceutical agents and various
other molecules that contain the 1, 1‐diaryl stereocenter. This has led to the development of …
other molecules that contain the 1, 1‐diaryl stereocenter. This has led to the development of …
Metal-free thiolation of sulfonyl hydrazone with thiophenol: synthesis of 4-thio-chroman and diarylmethyl thioethers
A simple, efficient, and transition metal-free approach was developed for accessing 4-thio-
substituted chroman and diarylmethyl thioethers from sulfonyl hydrazones. This protocol …
substituted chroman and diarylmethyl thioethers from sulfonyl hydrazones. This protocol …
Triflic Acid Catalyzed 1,6‐Conjugate Addition of Thiols to p‐Quinone Methides under Continuous‐Flow Conditions
AS Jadhav, RV Anand - European Journal of Organic Chemistry, 2017 - Wiley Online Library
Triflic Acid Catalyzed 1,6‐Conjugate Addition of Thiols to p‐Quinone Methides under
Continuous‐Flow Conditions - Jadhav - 2017 - European Journal of Organic Chemistry …
Continuous‐Flow Conditions - Jadhav - 2017 - European Journal of Organic Chemistry …
Synthesis of 7-Chloroquinoline derivatives using mixed lithium-magnesium reagents
VE Murie, PV Nicolino, T Dos Santos… - The Journal of …, 2021 - ACS Publications
We have prepared a library of functionalized quinolines through the magnesiation of 7-
chloroquinolines under mild conditions, employing both batch and continuous flow …
chloroquinolines under mild conditions, employing both batch and continuous flow …