Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …

This article describes commonly used experimental and clinical biomarkers of neuronal
injury and neurodegeneration for the evaluation of neuropathology and monitoring of …

Many people living with dementia and cognitive impairment have dysfunctional
mitochondrial and insulin-glucose metabolism resembling type 2 diabetes mellitus and old …

Alzheimer's disease (AD) is an age-associated, multifactorial neurodegenerative disorder
that is incurable. Despite recent success in treatments that partially improve symptomatic …

Monocytes are innate immune cells that sense environmental changes and participate in the
immunoregulation of autoimmune, neurologic, cardiovascular, and metabolic diseases as …

Abstract Background The prevalence of Alzheimer's disease, the most common type of
dementia, is continuously increasing. Many recent reports have indicated that immune …

Alzheimer's disease (AD) has shown altered immune responses in the periphery. We
studied P2X7 (a proinflammatory receptor and a scavenger receptor) and two integrins …

Background Alzheimer's disease (AD) is the most common form of dementia characterized
by a prominent cognitive deterioration of sufficient magnitude to impair daily living …

This paper reports the proceedings of a virtual meeting convened by the European
Interdisciplinary Council on Ageing (EICA), to discuss the involvement of infectious disorders …

Background Diet and chronic inflammation might play a major role in the pathogenesis of
mild cognitive impairment (MCI). In addition, peripheral blood leukocyte telomere length …