Therapeutic monoclonal antibodies for COVID-19 management: an update

VP Chavda, R Prajapati, D Lathigara… - Expert opinion on …, 2022 - Taylor & Francis
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
affected more than 529 million people, and today the world is facing different mutant strains …

Systemic sclerosis in the time of COVID-19

AM Hoffmann-Vold, O Distler, C Bruni… - The Lancet …, 2022 - thelancet.com
The COVID-19 pandemic represents one of the biggest challenges of the 21st century. In
addition to the general effect on society and health-care systems, patients with systemic …

Single-domain antibodies efficiently neutralize SARS-CoV-2 variants of concern

IA Favorskaya, DV Shcheblyakov… - Frontiers in …, 2022 - frontiersin.org
Virus-neutralizing antibodies are one of the few treatment options for COVID-19. The
evolution of SARS-CoV-2 virus has led to the emergence of virus variants with reduced …

A randomized clinical trial of regdanvimab in high-risk patients with mild-to-moderate coronavirus disease 2019

JY Kim, O Săndulescu, LL Preotescu… - Open forum …, 2022 - academic.oup.com
Background We evaluated clinical effectiveness of regdanvimab (CT-P59), a severe acute
respiratory syndrome coronavirus 2 neutralizing monoclonal antibody, in reducing disease …

Neutralizing activity against Omicron BA. 5 after tixagevimab/cilgavimab administration comparable to those after Omicron BA. 1/BA. 2 breakthrough infections

J Yang, G Won, JY Baek, YH Lee, H Kim… - Frontiers in …, 2023 - frontiersin.org
Introduction The effect of tixagevimab/cilgavimab (Evusheld™; AstraZeneca, UK) should be
evaluated in the context of concurrent outbreak situations. Methods For serologic …

[HTML][HTML] Regdanvimab in patients with mild-to-moderate SARS-CoV-2 infection: a propensity score–matched retrospective cohort study

S Lee, SO Lee, JE Lee, KH Kim, SH Lee… - International …, 2022 - Elsevier
Abstract Background Regdanvimab (CT-P59) is a neutralizing antibody authorized in
Republic of Korea for the treatment of adult patients with moderate or mild-COVID-19 who …

Effectiveness of regdanvimab treatment for SARS-CoV-2 delta variant, which exhibited decreased in vitro activity: a nationwide real-world multicenter cohort study

H Kim, YR Jang, JY Lee, JH Ko, JY Lee… - Frontiers in Cellular …, 2023 - frontiersin.org
Background Immune-evading severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) variants are emerging continuously. The clinical effectiveness of monoclonal antibody …

Druggable targets and therapeutic development for COVID-19

X Duan, LA Lacko, S Chen - Frontiers in Chemistry, 2022 - frontiersin.org
Coronavirus disease (COVID-19), which is caused by SARS-CoV-2, is the biggest challenge
to the global public health and economy in recent years. Until now, only limited therapeutic …

Screening, expression, and identification of nanobody against SARS-CoV-2 spike protein

Q Su, W Shi, X Huang, Y Wan, G Li, B Xing, ZP Xu… - Cells, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), an infectious disease that has become a serious burden on …

[HTML][HTML] Regdanvimab improves disease mortality and morbidity in patients with COVID-19: A meta-analysis

M Yang, T Li, L Jiang, Y Wang, C Tran… - The Journal of …, 2022 - ncbi.nlm.nih.gov
We read with great interest that biologic medications might be a promising therapeutic
option in COVID-19. 1 Neutralizing monoclonal antibodies such as regdanvimab can reduce …