Ultrahigh dose rate, FLASH radiotherapy has emerged as one of the most promising
innovations over the past decade in the field of radiation oncology, with the potential to …

Simple Summary FLASH radiotherapy (RT) delivering ultra-high dose rate radiation can
reduce normal tissue toxicity while effectively treating tumors. However, implementing …

Background and purpose The FLASH effect has been validated in different preclinical
experiments with electrons (eFLASH) and protons (pFLASH) operating at an average dose …

Abstract Background and Purpose Ultra-high dose-rate radiotherapy (FLASH) has been
shown to mitigate normal tissue toxicities associated with conventional dose rate …

This work demonstrates the precision achieved with thermoluminescence (TL) and optically
stimulated luminescence (OSL) detectors (TLDs and OSLDs) using a procedure that takes …

Purpose We conducted a multi-institutional dosimetric audit between FLASH and
conventional dose rate (CONV) electron irradiations by using an anatomically realistic 3 …

Objective. The aim of this work is to investigate the dose rate dependence of
thermoluminescence and optically stimulated luminescence detectors (TLDs and OSLDs) in …

Background and purpose The impact of radiotherapy (RT) at ultra high vs conventional dose
rate (FLASH vs CONV) on the generation and repair of DNA double strand breaks (DSBs) is …

The “FLASH effect” is an increased therapeutic index, that is, reduced normal tissue toxicity
for a given degree of anti-cancer efficacy, produced by ultra-rapid irradiation delivered on …

Preclinical studies have shown that radiotherapy treatments benefit from ultra-high dose rate
(UHDR) irradiations. These trigger the FLASH-effect, resulting in a strong decrease in …