Increasing brain disease incidence has become a common cause of disability and death
worldwide. Early diagnosis of brain diseases is crucial to improve the prognosis of patients …

Light in the near-infrared (NIR) region between 700–900 nm can penetrate deep into living
tissue, thereby offering a unique opportunity to use near-infrared fluorescence (NIRF) …

The growing field of stem cell therapy is moving toward clinical trials in a variety of
applications, particularly for neurological diseases. However, this translation of cell …

Recent studies have indicated that bone marrow stromal cells (BMSC) may improve
neurological function when transplanted into an animal model of CNS disorders, including …

Contrast-enhanced near-infrared spectroscopy (NIRS) with indocyanine green (ICG) can be
a valid non-invasive, continuous, bedside neuromonitoring tool. However, its usage in …

We study fluorescence lifetime of indocyanine green (ICG) using femtosecond laser and
sensitive detection based on time-correlated single-photon counting. A time-resolved …

Misfolding and aggregation of proteins are characteristics of a range of increasingly
prevalent neurodegenerative disorders including Alzheimer's and Parkinson's diseases. In …

Impairment of the blood–brain barrier (BBB) after cerebral ischemia leads to extravasation of
plasma constituents into the brain parenchyma. We describe a novel method using non …

Positron emission tomography (PET)–fluorescence imaging is an emerging field of
multimodality imaging seeking to attain synergy between the two techniques. The probes …

Inflammation is crucially involved in many diseases of the CNS. Immune cells may attack the
CNS, as in multiple sclerosis, and therefore be responsible for primary damage. Immune …